MDR/XDR-TB management of patients and contacts: Challenges facing the new decade. The 2020 clinical update by the Global Tuberculosis Network
The continuous flow of new research articles on MDR-TB diagnosis, treatment, prevention and rehabilitation requires frequent update of existing guidelines. This review is aimed at providing clinicians and public health staff with an updated and easy-to-consult document arising from consensus of Glo...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
2020
|
| Subjects: | |
| Online Access: | http://eprints.uanl.mx/20057/1/1-s2.0-S120197122030045X-main.pdf |
| _version_ | 1824415737015435264 |
|---|---|
| author | Migliori, Giovanni Battista Tiberi, Simon Zumla, Alimuddin Petersen, Eskild Chakaya, Jeremiah Muhwa Wejse, Christian Muñoz Torrico, Marcela Duarte, Raquel Alffenaar, Jan Willem Schaaf, H. Simon Marais, Ben J. Cirillo, Daniela Maria Alagna, Riccardo Rendón, Adrián Pontali, Emanuele Piubello, Alberto Figueroa, José Ferlazzo, Gabriella García Basteiro, Alberto Centis, Rosella Visca, Dina D’Ambrosio, Lia Sotgiu, Giovanni |
| author_facet | Migliori, Giovanni Battista Tiberi, Simon Zumla, Alimuddin Petersen, Eskild Chakaya, Jeremiah Muhwa Wejse, Christian Muñoz Torrico, Marcela Duarte, Raquel Alffenaar, Jan Willem Schaaf, H. Simon Marais, Ben J. Cirillo, Daniela Maria Alagna, Riccardo Rendón, Adrián Pontali, Emanuele Piubello, Alberto Figueroa, José Ferlazzo, Gabriella García Basteiro, Alberto Centis, Rosella Visca, Dina D’Ambrosio, Lia Sotgiu, Giovanni |
| author_sort | Migliori, Giovanni Battista |
| collection | Repositorio Institucional |
| description | The continuous flow of new research articles on MDR-TB diagnosis, treatment, prevention and rehabilitation requires frequent update of existing guidelines. This review is aimed at providing clinicians
and public health staff with an updated and easy-to-consult document arising from consensus of Global
Tuberculosis Network (GTN) experts.
The core published documents and guidelines have been reviewed, including the recently published
MDR-TB WHO rapid advice and ATS/CDC/ERS/IDSA guidelines.
After a rapid review of epidemiology and risk factors, the clinical priorities on MDR-TB diagnosis
(including whole genome sequencing and drug-susceptibility testing interpretations) and treatment
(treatment design and management, TB in children) are discussed. Furthermore, the review
comprehensively describes the latest information on contact tracing and LTBI management in MDR-
TB contacts, while providing guidance on post-treatment functional evaluation and rehabilitation of TB
sequelae, infection control and other public health priorities |
| format | Article |
| id | eprints-20057 |
| institution | UANL |
| language | English |
| publishDate | 2020 |
| record_format | eprints |
| spelling | eprints-200572022-03-03T02:52:53Z http://eprints.uanl.mx/20057/ MDR/XDR-TB management of patients and contacts: Challenges facing the new decade. The 2020 clinical update by the Global Tuberculosis Network Migliori, Giovanni Battista Tiberi, Simon Zumla, Alimuddin Petersen, Eskild Chakaya, Jeremiah Muhwa Wejse, Christian Muñoz Torrico, Marcela Duarte, Raquel Alffenaar, Jan Willem Schaaf, H. Simon Marais, Ben J. Cirillo, Daniela Maria Alagna, Riccardo Rendón, Adrián Pontali, Emanuele Piubello, Alberto Figueroa, José Ferlazzo, Gabriella García Basteiro, Alberto Centis, Rosella Visca, Dina D’Ambrosio, Lia Sotgiu, Giovanni RC Medicina Interna, Psiquiatría, Neurología The continuous flow of new research articles on MDR-TB diagnosis, treatment, prevention and rehabilitation requires frequent update of existing guidelines. This review is aimed at providing clinicians and public health staff with an updated and easy-to-consult document arising from consensus of Global Tuberculosis Network (GTN) experts. The core published documents and guidelines have been reviewed, including the recently published MDR-TB WHO rapid advice and ATS/CDC/ERS/IDSA guidelines. After a rapid review of epidemiology and risk factors, the clinical priorities on MDR-TB diagnosis (including whole genome sequencing and drug-susceptibility testing interpretations) and treatment (treatment design and management, TB in children) are discussed. Furthermore, the review comprehensively describes the latest information on contact tracing and LTBI management in MDR- TB contacts, while providing guidance on post-treatment functional evaluation and rehabilitation of TB sequelae, infection control and other public health priorities 2020 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/20057/1/1-s2.0-S120197122030045X-main.pdf http://eprints.uanl.mx/20057/1.haspreviewThumbnailVersion/1-s2.0-S120197122030045X-main.pdf Migliori, Giovanni Battista y Tiberi, Simon y Zumla, Alimuddin y Petersen, Eskild y Chakaya, Jeremiah Muhwa y Wejse, Christian y Muñoz Torrico, Marcela y Duarte, Raquel y Alffenaar, Jan Willem y Schaaf, H. Simon y Marais, Ben J. y Cirillo, Daniela Maria y Alagna, Riccardo y Rendón, Adrián y Pontali, Emanuele y Piubello, Alberto y Figueroa, José y Ferlazzo, Gabriella y García Basteiro, Alberto y Centis, Rosella y Visca, Dina y D’Ambrosio, Lia y Sotgiu, Giovanni (2020) MDR/XDR-TB management of patients and contacts: Challenges facing the new decade. The 2020 clinical update by the Global Tuberculosis Network. International Journal of Infectious Diseases, 92. S15-S25. ISSN 1201-9712 http://doi.org/10.1016/J.IJID.2020.01.042 doi:10.1016/J.IJID.2020.01.042 |
| spellingShingle | RC Medicina Interna, Psiquiatría, Neurología Migliori, Giovanni Battista Tiberi, Simon Zumla, Alimuddin Petersen, Eskild Chakaya, Jeremiah Muhwa Wejse, Christian Muñoz Torrico, Marcela Duarte, Raquel Alffenaar, Jan Willem Schaaf, H. Simon Marais, Ben J. Cirillo, Daniela Maria Alagna, Riccardo Rendón, Adrián Pontali, Emanuele Piubello, Alberto Figueroa, José Ferlazzo, Gabriella García Basteiro, Alberto Centis, Rosella Visca, Dina D’Ambrosio, Lia Sotgiu, Giovanni MDR/XDR-TB management of patients and contacts: Challenges facing the new decade. The 2020 clinical update by the Global Tuberculosis Network |
| thumbnail | https://rediab.uanl.mx/themes/sandal5/images/online.png |
| title | MDR/XDR-TB management of patients and contacts: Challenges facing the new decade. The 2020 clinical update by the Global Tuberculosis Network |
| title_full | MDR/XDR-TB management of patients and contacts: Challenges facing the new decade. The 2020 clinical update by the Global Tuberculosis Network |
| title_fullStr | MDR/XDR-TB management of patients and contacts: Challenges facing the new decade. The 2020 clinical update by the Global Tuberculosis Network |
| title_full_unstemmed | MDR/XDR-TB management of patients and contacts: Challenges facing the new decade. The 2020 clinical update by the Global Tuberculosis Network |
| title_short | MDR/XDR-TB management of patients and contacts: Challenges facing the new decade. The 2020 clinical update by the Global Tuberculosis Network |
| title_sort | mdr xdr tb management of patients and contacts challenges facing the new decade the 2020 clinical update by the global tuberculosis network |
| topic | RC Medicina Interna, Psiquiatría, Neurología |
| url | http://eprints.uanl.mx/20057/1/1-s2.0-S120197122030045X-main.pdf |
| work_keys_str_mv | AT migliorigiovannibattista mdrxdrtbmanagementofpatientsandcontactschallengesfacingthenewdecadethe2020clinicalupdatebytheglobaltuberculosisnetwork AT tiberisimon mdrxdrtbmanagementofpatientsandcontactschallengesfacingthenewdecadethe2020clinicalupdatebytheglobaltuberculosisnetwork AT zumlaalimuddin mdrxdrtbmanagementofpatientsandcontactschallengesfacingthenewdecadethe2020clinicalupdatebytheglobaltuberculosisnetwork AT peterseneskild mdrxdrtbmanagementofpatientsandcontactschallengesfacingthenewdecadethe2020clinicalupdatebytheglobaltuberculosisnetwork AT chakayajeremiahmuhwa mdrxdrtbmanagementofpatientsandcontactschallengesfacingthenewdecadethe2020clinicalupdatebytheglobaltuberculosisnetwork AT wejsechristian mdrxdrtbmanagementofpatientsandcontactschallengesfacingthenewdecadethe2020clinicalupdatebytheglobaltuberculosisnetwork AT munoztorricomarcela mdrxdrtbmanagementofpatientsandcontactschallengesfacingthenewdecadethe2020clinicalupdatebytheglobaltuberculosisnetwork AT duarteraquel mdrxdrtbmanagementofpatientsandcontactschallengesfacingthenewdecadethe2020clinicalupdatebytheglobaltuberculosisnetwork AT alffenaarjanwillem mdrxdrtbmanagementofpatientsandcontactschallengesfacingthenewdecadethe2020clinicalupdatebytheglobaltuberculosisnetwork AT schaafhsimon mdrxdrtbmanagementofpatientsandcontactschallengesfacingthenewdecadethe2020clinicalupdatebytheglobaltuberculosisnetwork AT maraisbenj mdrxdrtbmanagementofpatientsandcontactschallengesfacingthenewdecadethe2020clinicalupdatebytheglobaltuberculosisnetwork AT cirillodanielamaria mdrxdrtbmanagementofpatientsandcontactschallengesfacingthenewdecadethe2020clinicalupdatebytheglobaltuberculosisnetwork AT alagnariccardo mdrxdrtbmanagementofpatientsandcontactschallengesfacingthenewdecadethe2020clinicalupdatebytheglobaltuberculosisnetwork AT rendonadrian mdrxdrtbmanagementofpatientsandcontactschallengesfacingthenewdecadethe2020clinicalupdatebytheglobaltuberculosisnetwork AT pontaliemanuele mdrxdrtbmanagementofpatientsandcontactschallengesfacingthenewdecadethe2020clinicalupdatebytheglobaltuberculosisnetwork AT piubelloalberto mdrxdrtbmanagementofpatientsandcontactschallengesfacingthenewdecadethe2020clinicalupdatebytheglobaltuberculosisnetwork AT figueroajose mdrxdrtbmanagementofpatientsandcontactschallengesfacingthenewdecadethe2020clinicalupdatebytheglobaltuberculosisnetwork AT ferlazzogabriella mdrxdrtbmanagementofpatientsandcontactschallengesfacingthenewdecadethe2020clinicalupdatebytheglobaltuberculosisnetwork AT garciabasteiroalberto mdrxdrtbmanagementofpatientsandcontactschallengesfacingthenewdecadethe2020clinicalupdatebytheglobaltuberculosisnetwork AT centisrosella mdrxdrtbmanagementofpatientsandcontactschallengesfacingthenewdecadethe2020clinicalupdatebytheglobaltuberculosisnetwork AT viscadina mdrxdrtbmanagementofpatientsandcontactschallengesfacingthenewdecadethe2020clinicalupdatebytheglobaltuberculosisnetwork AT dambrosiolia mdrxdrtbmanagementofpatientsandcontactschallengesfacingthenewdecadethe2020clinicalupdatebytheglobaltuberculosisnetwork AT sotgiugiovanni mdrxdrtbmanagementofpatientsandcontactschallengesfacingthenewdecadethe2020clinicalupdatebytheglobaltuberculosisnetwork |