| Summary: | The continuous flow of new research articles on MDR-TB diagnosis, treatment, prevention and rehabilitation requires frequent update of existing guidelines. This review is aimed at providing clinicians
and public health staff with an updated and easy-to-consult document arising from consensus of Global
Tuberculosis Network (GTN) experts.
The core published documents and guidelines have been reviewed, including the recently published
MDR-TB WHO rapid advice and ATS/CDC/ERS/IDSA guidelines.
After a rapid review of epidemiology and risk factors, the clinical priorities on MDR-TB diagnosis
(including whole genome sequencing and drug-susceptibility testing interpretations) and treatment
(treatment design and management, TB in children) are discussed. Furthermore, the review
comprehensively describes the latest information on contact tracing and LTBI management in MDR-
TB contacts, while providing guidance on post-treatment functional evaluation and rehabilitation of TB
sequelae, infection control and other public health priorities
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