Biological Activities of Extracts from Aerial Parts of Salvia pachyphylla Epling Ex Munz
Abstract: The antioxidant, antimicrobial, antiproliferative, and enzyme inhibitory properties of five extracts from aerial parts of Salvia pachyphylla Epling ex Munz were examined to assess the prospective of this plant as a source of natural products with therapeutic potential. These properties were...
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| Format: | Article |
| Language: | English |
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2018
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| Online Access: | http://eprints.uanl.mx/15968/1/41.pdf |
| _version_ | 1824414448503226368 |
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| author | Almada Taylor, Gabriela Díaz Rubio, Laura Salazar Aranda, Ricardo Waksman de Torres, Noemí Uranga Solis, Carla Delgadillo Rodríguez, José Ramos, Marco Padrón, José Hernández Martínez, Rufina Córdova Guerrero, Iván |
| author_facet | Almada Taylor, Gabriela Díaz Rubio, Laura Salazar Aranda, Ricardo Waksman de Torres, Noemí Uranga Solis, Carla Delgadillo Rodríguez, José Ramos, Marco Padrón, José Hernández Martínez, Rufina Córdova Guerrero, Iván |
| author_sort | Almada Taylor, Gabriela |
| collection | Repositorio Institucional |
| description | Abstract: The antioxidant, antimicrobial, antiproliferative, and enzyme inhibitory properties of five extracts from aerial parts of Salvia pachyphylla Epling ex Munz were examined to assess the prospective of this plant as a source of natural products with therapeutic potential. These properties were analyzed by performing a set of standard assays. The extract obtained with dichloromethane showed the most variety of components, as they yielded promising results in all completed assays. Furthermore,theextractobtainedwithethylacetateexhibitedthegreatestantioxidantactivity,aswell as the best xanthine oxidase inhibitory activity. Remarkably, both extracts obtained with n-hexane or dichloromethane revealed significant antimicrobial activity against the Gram-positive bacteria; additionally, they showed greater antiproliferative activity against three representative cell lines of the most common types of cancers in women worldwide, and against a cell line that exemplifies cancers that typically develop drug resistance. Despite that, other extracts were less active, such as the methanolic or aqueous; their results are promising for the isolation and identification of novel bioactive molecules. |
| format | Article |
| id | eprints-15968 |
| institution | UANL |
| language | English |
| publishDate | 2018 |
| record_format | eprints |
| spelling | eprints-159682020-06-18T15:57:30Z http://eprints.uanl.mx/15968/ Biological Activities of Extracts from Aerial Parts of Salvia pachyphylla Epling Ex Munz Almada Taylor, Gabriela Díaz Rubio, Laura Salazar Aranda, Ricardo Waksman de Torres, Noemí Uranga Solis, Carla Delgadillo Rodríguez, José Ramos, Marco Padrón, José Hernández Martínez, Rufina Córdova Guerrero, Iván RM Terapéutica, Farmacología Abstract: The antioxidant, antimicrobial, antiproliferative, and enzyme inhibitory properties of five extracts from aerial parts of Salvia pachyphylla Epling ex Munz were examined to assess the prospective of this plant as a source of natural products with therapeutic potential. These properties were analyzed by performing a set of standard assays. The extract obtained with dichloromethane showed the most variety of components, as they yielded promising results in all completed assays. Furthermore,theextractobtainedwithethylacetateexhibitedthegreatestantioxidantactivity,aswell as the best xanthine oxidase inhibitory activity. Remarkably, both extracts obtained with n-hexane or dichloromethane revealed significant antimicrobial activity against the Gram-positive bacteria; additionally, they showed greater antiproliferative activity against three representative cell lines of the most common types of cancers in women worldwide, and against a cell line that exemplifies cancers that typically develop drug resistance. Despite that, other extracts were less active, such as the methanolic or aqueous; their results are promising for the isolation and identification of novel bioactive molecules. 2018-11-23 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/15968/1/41.pdf http://eprints.uanl.mx/15968/1.haspreviewThumbnailVersion/41.pdf Almada Taylor, Gabriela y Díaz Rubio, Laura y Salazar Aranda, Ricardo y Waksman de Torres, Noemí y Uranga Solis, Carla y Delgadillo Rodríguez, José y Ramos, Marco y Padrón, José y Hernández Martínez, Rufina y Córdova Guerrero, Iván (2018) Biological Activities of Extracts from Aerial Parts of Salvia pachyphylla Epling Ex Munz. Plants, 7 (4). pp. 1-13. ISSN 2223-7747 http://doi.org/10.3390/plants7040105 doi:10.3390/plants7040105 |
| spellingShingle | RM Terapéutica, Farmacología Almada Taylor, Gabriela Díaz Rubio, Laura Salazar Aranda, Ricardo Waksman de Torres, Noemí Uranga Solis, Carla Delgadillo Rodríguez, José Ramos, Marco Padrón, José Hernández Martínez, Rufina Córdova Guerrero, Iván Biological Activities of Extracts from Aerial Parts of Salvia pachyphylla Epling Ex Munz |
| thumbnail | https://rediab.uanl.mx/themes/sandal5/images/online.png |
| title | Biological Activities of Extracts from Aerial Parts of Salvia pachyphylla Epling Ex Munz |
| title_full | Biological Activities of Extracts from Aerial Parts of Salvia pachyphylla Epling Ex Munz |
| title_fullStr | Biological Activities of Extracts from Aerial Parts of Salvia pachyphylla Epling Ex Munz |
| title_full_unstemmed | Biological Activities of Extracts from Aerial Parts of Salvia pachyphylla Epling Ex Munz |
| title_short | Biological Activities of Extracts from Aerial Parts of Salvia pachyphylla Epling Ex Munz |
| title_sort | biological activities of extracts from aerial parts of salvia pachyphylla epling ex munz |
| topic | RM Terapéutica, Farmacología |
| url | http://eprints.uanl.mx/15968/1/41.pdf |
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