A pharmacogenetic pilot study reveals MTHFR, DRD3, and MDR1 polymorphisms as biomarker candidates for slow atorvastatin metabolizers

Background: The genetic variation underlying atorvastatin (ATV) pharmacokinetics was evaluated in a Mexican population. Aims of this study were: 1) to reveal the frequency of 87 polymorphisms in 36 genes related to drug metabolism in healthy Mexican volunteers, 2) to evaluate the impact of these pol...

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Main Authors:	León Cachón, Rafael B. R., Ascacio Martínez, Jorge Ángel Isidro, Gamino Peña, María E., Cerda Flores, Ricardo Martín, Meester, Irene, Gallardo Blanco, Hugo Leonid, Gómez Silva, Magdalena, Piñeyro Garza, Everardo, Barrera Saldaña, Hugo Alberto
Format:	Article
Language:	English
Published:	BMC 2016
Online Access:	http://eprints.uanl.mx/14840/1/55.pdf