A pharmacogenetic pilot study reveals MTHFR, DRD3, and MDR1 polymorphisms as biomarker candidates for slow atorvastatin metabolizers
Background: The genetic variation underlying atorvastatin (ATV) pharmacokinetics was evaluated in a Mexican population. Aims of this study were: 1) to reveal the frequency of 87 polymorphisms in 36 genes related to drug metabolism in healthy Mexican volunteers, 2) to evaluate the impact of these pol...
| Autores principales: | , , , , , , , , |
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| Format: | Artículo |
| Jezik: | English |
| Izdano: |
BMC
2016
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| Online dostop: | http://eprints.uanl.mx/14840/1/55.pdf |