Plasmonic/Magnetic Multifunctional nanoplatform for Cancer Theranostics

Cancer is the second leading disease which causes major mortality and morbidity worldwide1 . In cancer therapy, it is crucial to increase the drug specificity and drug efficacy to minimise or completely eradicate significant side-effects on patients2 . Cancer nanotherapeutics overcome many serio...

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Autores principales: Ravichandran, M., Oza, Goldie, Velumani, S., Ramirez, Jose Tapia, García Sierra, Francisco, Andrade, Norma Barragan, Vera, A., Leija, L., Garza Navarro, Marco Antonio
Formato: Artículo
Lenguaje:inglés
Publicado: 2016
Materias:
Acceso en línea:http://eprints.uanl.mx/14754/1/3.pdf
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author Ravichandran, M.
Oza, Goldie
Velumani, S.
Ramirez, Jose Tapia
García Sierra, Francisco
Andrade, Norma Barragan
Vera, A.
Leija, L.
Garza Navarro, Marco Antonio
author_facet Ravichandran, M.
Oza, Goldie
Velumani, S.
Ramirez, Jose Tapia
García Sierra, Francisco
Andrade, Norma Barragan
Vera, A.
Leija, L.
Garza Navarro, Marco Antonio
author_sort Ravichandran, M.
collection Repositorio Institucional
description Cancer is the second leading disease which causes major mortality and morbidity worldwide1 . In cancer therapy, it is crucial to increase the drug specificity and drug efficacy to minimise or completely eradicate significant side-effects on patients2 . Cancer nanotherapeutics overcome many serious drawbacks of chemotherapy such as non-specific targeting, lower efficacy, insolubility of drug moieties in water and oral bioavailability3 . Accordingly, Superparamagnetic Iron Oxide Nanoparticles (SPIONs) are exploited as an important nanomaterial for cancer detection as well as therapeutics4 . Such magnetic nanoparticles (NPs) gained its momentum because of their single-domain ordering along with their large surface to volume ratio (providing large surface area for attachment of biological entities). Hence, this property makes them a suitable candidate as a contrast agent, drug-carrying cargo and hyperthermal agent5 .
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spelling eprints-147542021-06-10T15:04:02Z http://eprints.uanl.mx/14754/ Plasmonic/Magnetic Multifunctional nanoplatform for Cancer Theranostics Ravichandran, M. Oza, Goldie Velumani, S. Ramirez, Jose Tapia García Sierra, Francisco Andrade, Norma Barragan Vera, A. Leija, L. Garza Navarro, Marco Antonio T Tecnología en General Cancer is the second leading disease which causes major mortality and morbidity worldwide1 . In cancer therapy, it is crucial to increase the drug specificity and drug efficacy to minimise or completely eradicate significant side-effects on patients2 . Cancer nanotherapeutics overcome many serious drawbacks of chemotherapy such as non-specific targeting, lower efficacy, insolubility of drug moieties in water and oral bioavailability3 . Accordingly, Superparamagnetic Iron Oxide Nanoparticles (SPIONs) are exploited as an important nanomaterial for cancer detection as well as therapeutics4 . Such magnetic nanoparticles (NPs) gained its momentum because of their single-domain ordering along with their large surface to volume ratio (providing large surface area for attachment of biological entities). Hence, this property makes them a suitable candidate as a contrast agent, drug-carrying cargo and hyperthermal agent5 . 2016 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/14754/1/3.pdf http://eprints.uanl.mx/14754/1.haspreviewThumbnailVersion/3.pdf Ravichandran, M. y Oza, Goldie y Velumani, S. y Ramirez, Jose Tapia y García Sierra, Francisco y Andrade, Norma Barragan y Vera, A. y Leija, L. y Garza Navarro, Marco Antonio (2016) Plasmonic/Magnetic Multifunctional nanoplatform for Cancer Theranostics. Scientific Reports, 6 (1). ISSN 2045-2322 http://doi.org/10.1038/srep34874 doi:10.1038/srep34874
spellingShingle T Tecnología en General
Ravichandran, M.
Oza, Goldie
Velumani, S.
Ramirez, Jose Tapia
García Sierra, Francisco
Andrade, Norma Barragan
Vera, A.
Leija, L.
Garza Navarro, Marco Antonio
Plasmonic/Magnetic Multifunctional nanoplatform for Cancer Theranostics
thumbnail https://rediab.uanl.mx/themes/sandal5/images/online.png
title Plasmonic/Magnetic Multifunctional nanoplatform for Cancer Theranostics
title_full Plasmonic/Magnetic Multifunctional nanoplatform for Cancer Theranostics
title_fullStr Plasmonic/Magnetic Multifunctional nanoplatform for Cancer Theranostics
title_full_unstemmed Plasmonic/Magnetic Multifunctional nanoplatform for Cancer Theranostics
title_short Plasmonic/Magnetic Multifunctional nanoplatform for Cancer Theranostics
title_sort plasmonic magnetic multifunctional nanoplatform for cancer theranostics
topic T Tecnología en General
url http://eprints.uanl.mx/14754/1/3.pdf
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