Plasmonic/Magnetic Multifunctional nanoplatform for Cancer Theranostics
Cancer is the second leading disease which causes major mortality and morbidity worldwide1 . In cancer therapy, it is crucial to increase the drug specificity and drug efficacy to minimise or completely eradicate significant side-effects on patients2 . Cancer nanotherapeutics overcome many serio...
Autores principales: | , , , , , , , , |
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Formato: | Artículo |
Lenguaje: | inglés |
Publicado: |
2016
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Materias: | |
Acceso en línea: | http://eprints.uanl.mx/14754/1/3.pdf |
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author | Ravichandran, M. Oza, Goldie Velumani, S. Ramirez, Jose Tapia García Sierra, Francisco Andrade, Norma Barragan Vera, A. Leija, L. Garza Navarro, Marco Antonio |
author_facet | Ravichandran, M. Oza, Goldie Velumani, S. Ramirez, Jose Tapia García Sierra, Francisco Andrade, Norma Barragan Vera, A. Leija, L. Garza Navarro, Marco Antonio |
author_sort | Ravichandran, M. |
collection | Repositorio Institucional |
description | Cancer is the second leading disease which causes major mortality and morbidity worldwide1
. In cancer therapy, it is
crucial to increase the drug specificity and drug efficacy to minimise or completely eradicate significant side-effects on
patients2
. Cancer nanotherapeutics overcome many serious drawbacks of chemotherapy such as non-specific targeting,
lower efficacy, insolubility of drug moieties in water and oral bioavailability3
. Accordingly, Superparamagnetic Iron
Oxide Nanoparticles (SPIONs) are exploited as an important nanomaterial for cancer detection as well as therapeutics4
.
Such magnetic nanoparticles (NPs) gained its momentum because of their single-domain ordering along with their
large surface to volume ratio (providing large surface area for attachment of biological entities). Hence, this property
makes them a suitable candidate as a contrast agent, drug-carrying cargo and hyperthermal agent5
. |
format | Article |
id | eprints-14754 |
institution | UANL |
language | English |
publishDate | 2016 |
record_format | eprints |
spelling | eprints-147542021-06-10T15:04:02Z http://eprints.uanl.mx/14754/ Plasmonic/Magnetic Multifunctional nanoplatform for Cancer Theranostics Ravichandran, M. Oza, Goldie Velumani, S. Ramirez, Jose Tapia García Sierra, Francisco Andrade, Norma Barragan Vera, A. Leija, L. Garza Navarro, Marco Antonio T Tecnología en General Cancer is the second leading disease which causes major mortality and morbidity worldwide1 . In cancer therapy, it is crucial to increase the drug specificity and drug efficacy to minimise or completely eradicate significant side-effects on patients2 . Cancer nanotherapeutics overcome many serious drawbacks of chemotherapy such as non-specific targeting, lower efficacy, insolubility of drug moieties in water and oral bioavailability3 . Accordingly, Superparamagnetic Iron Oxide Nanoparticles (SPIONs) are exploited as an important nanomaterial for cancer detection as well as therapeutics4 . Such magnetic nanoparticles (NPs) gained its momentum because of their single-domain ordering along with their large surface to volume ratio (providing large surface area for attachment of biological entities). Hence, this property makes them a suitable candidate as a contrast agent, drug-carrying cargo and hyperthermal agent5 . 2016 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/14754/1/3.pdf http://eprints.uanl.mx/14754/1.haspreviewThumbnailVersion/3.pdf Ravichandran, M. y Oza, Goldie y Velumani, S. y Ramirez, Jose Tapia y García Sierra, Francisco y Andrade, Norma Barragan y Vera, A. y Leija, L. y Garza Navarro, Marco Antonio (2016) Plasmonic/Magnetic Multifunctional nanoplatform for Cancer Theranostics. Scientific Reports, 6 (1). ISSN 2045-2322 http://doi.org/10.1038/srep34874 doi:10.1038/srep34874 |
spellingShingle | T Tecnología en General Ravichandran, M. Oza, Goldie Velumani, S. Ramirez, Jose Tapia García Sierra, Francisco Andrade, Norma Barragan Vera, A. Leija, L. Garza Navarro, Marco Antonio Plasmonic/Magnetic Multifunctional nanoplatform for Cancer Theranostics |
thumbnail | https://rediab.uanl.mx/themes/sandal5/images/online.png |
title | Plasmonic/Magnetic Multifunctional nanoplatform for Cancer Theranostics |
title_full | Plasmonic/Magnetic Multifunctional nanoplatform for Cancer Theranostics |
title_fullStr | Plasmonic/Magnetic Multifunctional nanoplatform for Cancer Theranostics |
title_full_unstemmed | Plasmonic/Magnetic Multifunctional nanoplatform for Cancer Theranostics |
title_short | Plasmonic/Magnetic Multifunctional nanoplatform for Cancer Theranostics |
title_sort | plasmonic magnetic multifunctional nanoplatform for cancer theranostics |
topic | T Tecnología en General |
url | http://eprints.uanl.mx/14754/1/3.pdf |
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