Gastrointestinal Langerhans cell histiocytosis responding to cladribine and imatinib mesylate

Gastrointestinal involvement in Langerhans cells histiocytosis (LCH) is extremely rare. An optimal treatment regimen is not defined yet and its prognosis is relatively poor. Cladribine, and more recently, Imatinib mesylate (IM) have been recommended as treatment options in refractory LCH. Here we pr...

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Autores principales: Agreda Vásquez, Gladys Patricia, Popoca Barriga, Ulises, Oviedo, Edgar, Lome Maldonado, Carmen, Sánchez Guerrero, Sergio Arturo
Formato: Artículo
Lenguaje:inglés
Publicado: UANL Facultad de Medicina 2010
Acceso en línea:http://eprints.uanl.mx/8449/1/Gastrointestinal%20Langerhans.pdf
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author Agreda Vásquez, Gladys Patricia
Popoca Barriga, Ulises
Oviedo, Edgar
Lome Maldonado, Carmen
Sánchez Guerrero, Sergio Arturo
author_facet Agreda Vásquez, Gladys Patricia
Popoca Barriga, Ulises
Oviedo, Edgar
Lome Maldonado, Carmen
Sánchez Guerrero, Sergio Arturo
author_sort Agreda Vásquez, Gladys Patricia
collection Repositorio Institucional
description Gastrointestinal involvement in Langerhans cells histiocytosis (LCH) is extremely rare. An optimal treatment regimen is not defined yet and its prognosis is relatively poor. Cladribine, and more recently, Imatinib mesylate (IM) have been recommended as treatment options in refractory LCH. Here we present a case of gastrointestinal involvement in an adult patient with LCH refractory to several treatment regimens who responded nicely to cladribine and currently treated with IM 300 mg/day, as maintenance, for the last 24 months.
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spelling eprints-84492016-01-20T03:55:01Z http://eprints.uanl.mx/8449/ Gastrointestinal Langerhans cell histiocytosis responding to cladribine and imatinib mesylate Agreda Vásquez, Gladys Patricia Popoca Barriga, Ulises Oviedo, Edgar Lome Maldonado, Carmen Sánchez Guerrero, Sergio Arturo Gastrointestinal involvement in Langerhans cells histiocytosis (LCH) is extremely rare. An optimal treatment regimen is not defined yet and its prognosis is relatively poor. Cladribine, and more recently, Imatinib mesylate (IM) have been recommended as treatment options in refractory LCH. Here we present a case of gastrointestinal involvement in an adult patient with LCH refractory to several treatment regimens who responded nicely to cladribine and currently treated with IM 300 mg/day, as maintenance, for the last 24 months. UANL Facultad de Medicina 2010 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/8449/1/Gastrointestinal%20Langerhans.pdf http://eprints.uanl.mx/8449/1.haspreviewThumbnailVersion/Gastrointestinal%20Langerhans.pdf Agreda Vásquez, Gladys Patricia y Popoca Barriga, Ulises y Oviedo, Edgar y Lome Maldonado, Carmen y Sánchez Guerrero, Sergio Arturo (2010) Gastrointestinal Langerhans cell histiocytosis responding to cladribine and imatinib mesylate. Medicina universitaria, 12 (47). pp. 131-134. ISSN 1665-5796
spellingShingle Agreda Vásquez, Gladys Patricia
Popoca Barriga, Ulises
Oviedo, Edgar
Lome Maldonado, Carmen
Sánchez Guerrero, Sergio Arturo
Gastrointestinal Langerhans cell histiocytosis responding to cladribine and imatinib mesylate
thumbnail https://rediab.uanl.mx/themes/sandal5/images/online.png
title Gastrointestinal Langerhans cell histiocytosis responding to cladribine and imatinib mesylate
title_full Gastrointestinal Langerhans cell histiocytosis responding to cladribine and imatinib mesylate
title_fullStr Gastrointestinal Langerhans cell histiocytosis responding to cladribine and imatinib mesylate
title_full_unstemmed Gastrointestinal Langerhans cell histiocytosis responding to cladribine and imatinib mesylate
title_short Gastrointestinal Langerhans cell histiocytosis responding to cladribine and imatinib mesylate
title_sort gastrointestinal langerhans cell histiocytosis responding to cladribine and imatinib mesylate
url http://eprints.uanl.mx/8449/1/Gastrointestinal%20Langerhans.pdf
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