Gastrointestinal Langerhans cell histiocytosis responding to cladribine and imatinib mesylate
Gastrointestinal involvement in Langerhans cells histiocytosis (LCH) is extremely rare. An optimal treatment regimen is not defined yet and its prognosis is relatively poor. Cladribine, and more recently, Imatinib mesylate (IM) have been recommended as treatment options in refractory LCH. Here we pr...
| Autores principales: | , , , , |
|---|---|
| Formato: | Artículo |
| Lenguaje: | inglés |
| Publicado: |
UANL Facultad de Medicina
2010
|
| Acceso en línea: | http://eprints.uanl.mx/8449/1/Gastrointestinal%20Langerhans.pdf |
| _version_ | 1824370715659337728 |
|---|---|
| author | Agreda Vásquez, Gladys Patricia Popoca Barriga, Ulises Oviedo, Edgar Lome Maldonado, Carmen Sánchez Guerrero, Sergio Arturo |
| author_facet | Agreda Vásquez, Gladys Patricia Popoca Barriga, Ulises Oviedo, Edgar Lome Maldonado, Carmen Sánchez Guerrero, Sergio Arturo |
| author_sort | Agreda Vásquez, Gladys Patricia |
| collection | Repositorio Institucional |
| description | Gastrointestinal involvement in Langerhans cells histiocytosis (LCH) is extremely rare. An optimal treatment regimen is not defined yet and its prognosis is relatively poor. Cladribine, and more recently, Imatinib mesylate (IM) have been recommended as treatment options in refractory LCH. Here we present a case of gastrointestinal involvement in an adult patient with LCH refractory to several treatment regimens who responded nicely to cladribine and currently treated with IM 300 mg/day, as maintenance, for the last 24 months. |
| format | Article |
| id | eprints-8449 |
| institution | UANL |
| language | English |
| publishDate | 2010 |
| publisher | UANL Facultad de Medicina |
| record_format | eprints |
| spelling | eprints-84492016-01-20T03:55:01Z http://eprints.uanl.mx/8449/ Gastrointestinal Langerhans cell histiocytosis responding to cladribine and imatinib mesylate Agreda Vásquez, Gladys Patricia Popoca Barriga, Ulises Oviedo, Edgar Lome Maldonado, Carmen Sánchez Guerrero, Sergio Arturo Gastrointestinal involvement in Langerhans cells histiocytosis (LCH) is extremely rare. An optimal treatment regimen is not defined yet and its prognosis is relatively poor. Cladribine, and more recently, Imatinib mesylate (IM) have been recommended as treatment options in refractory LCH. Here we present a case of gastrointestinal involvement in an adult patient with LCH refractory to several treatment regimens who responded nicely to cladribine and currently treated with IM 300 mg/day, as maintenance, for the last 24 months. UANL Facultad de Medicina 2010 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/8449/1/Gastrointestinal%20Langerhans.pdf http://eprints.uanl.mx/8449/1.haspreviewThumbnailVersion/Gastrointestinal%20Langerhans.pdf Agreda Vásquez, Gladys Patricia y Popoca Barriga, Ulises y Oviedo, Edgar y Lome Maldonado, Carmen y Sánchez Guerrero, Sergio Arturo (2010) Gastrointestinal Langerhans cell histiocytosis responding to cladribine and imatinib mesylate. Medicina universitaria, 12 (47). pp. 131-134. ISSN 1665-5796 |
| spellingShingle | Agreda Vásquez, Gladys Patricia Popoca Barriga, Ulises Oviedo, Edgar Lome Maldonado, Carmen Sánchez Guerrero, Sergio Arturo Gastrointestinal Langerhans cell histiocytosis responding to cladribine and imatinib mesylate |
| thumbnail | https://rediab.uanl.mx/themes/sandal5/images/online.png |
| title | Gastrointestinal Langerhans cell histiocytosis responding to cladribine and imatinib mesylate |
| title_full | Gastrointestinal Langerhans cell histiocytosis responding to cladribine and imatinib mesylate |
| title_fullStr | Gastrointestinal Langerhans cell histiocytosis responding to cladribine and imatinib mesylate |
| title_full_unstemmed | Gastrointestinal Langerhans cell histiocytosis responding to cladribine and imatinib mesylate |
| title_short | Gastrointestinal Langerhans cell histiocytosis responding to cladribine and imatinib mesylate |
| title_sort | gastrointestinal langerhans cell histiocytosis responding to cladribine and imatinib mesylate |
| url | http://eprints.uanl.mx/8449/1/Gastrointestinal%20Langerhans.pdf |
| work_keys_str_mv | AT agredavasquezgladyspatricia gastrointestinallangerhanscellhistiocytosisrespondingtocladribineandimatinibmesylate AT popocabarrigaulises gastrointestinallangerhanscellhistiocytosisrespondingtocladribineandimatinibmesylate AT oviedoedgar gastrointestinallangerhanscellhistiocytosisrespondingtocladribineandimatinibmesylate AT lomemaldonadocarmen gastrointestinallangerhanscellhistiocytosisrespondingtocladribineandimatinibmesylate AT sanchezguerrerosergioarturo gastrointestinallangerhanscellhistiocytosisrespondingtocladribineandimatinibmesylate |