SARS-CoV-2 another kind of liver aggressor, how does it do that?

Clinical manifestations of SARS-CoV-2 infection include more frequently fever and cough, but complications (such as pneumonia, respiratory distress syndrome, and multiorgan failure) can occur in persons with additional comorbidities. Liver dysfunction is one of the most striking affections among pat...

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Detalles Bibliográficos
Autores principales: Lozano Sepúlveda, Sonia Amelia, Galan Huerta, Kame, Martínez Acuña, Natalia, Arellanos Soto, Daniel, Rivas Estilla, Ana María
Formato: Artículo
Lenguaje:inglés
Publicado: Elsevier España 2020
Acceso en línea:http://eprints.uanl.mx/30149/1/30149.pdf
Descripción
Sumario:Clinical manifestations of SARS-CoV-2 infection include more frequently fever and cough, but complications (such as pneumonia, respiratory distress syndrome, and multiorgan failure) can occur in persons with additional comorbidities. Liver dysfunction is one of the most striking affections among patients suggesting that SARS-CoV-2 may represent a new king of liver aggressor. However, the molecular process underlying this phenomenon is still unclear. In this work, we overview the most recent findings between the molecular biology of the virus, pathogenic mechanisms, and its relationship to liver disease observed in patients.