SARS-CoV-2 another kind of liver aggressor, how does it do that?

Clinical manifestations of SARS-CoV-2 infection include more frequently fever and cough, but complications (such as pneumonia, respiratory distress syndrome, and multiorgan failure) can occur in persons with additional comorbidities. Liver dysfunction is one of the most striking affections among pat...

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Bibliographic Details
Main Authors: Lozano Sepúlveda, Sonia Amelia, Galan Huerta, Kame, Martínez Acuña, Natalia, Arellanos Soto, Daniel, Rivas Estilla, Ana María
Format: Article
Language:English
Published: Elsevier España 2020
Online Access:http://eprints.uanl.mx/30149/1/30149.pdf
Description
Summary:Clinical manifestations of SARS-CoV-2 infection include more frequently fever and cough, but complications (such as pneumonia, respiratory distress syndrome, and multiorgan failure) can occur in persons with additional comorbidities. Liver dysfunction is one of the most striking affections among patients suggesting that SARS-CoV-2 may represent a new king of liver aggressor. However, the molecular process underlying this phenomenon is still unclear. In this work, we overview the most recent findings between the molecular biology of the virus, pathogenic mechanisms, and its relationship to liver disease observed in patients.