Cotransfected human chondrocytes: over-expression of IGF-I and SOX9 enhances the synthesis of cartilage matrix components collagen-II and glycosaminoglycans

Damage to cartilage causes a loss of type II collagen (Col-II) and glycosaminoglycans (GAG). To restore the original cartilage architecture, cell factors that stimulate Col-II and GAG production are needed. Insulin-like growth factor I (IGF-I) and transcription factor SOX9 are essential for the synt...

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Bibliographic Details

Main Authors:	Simental Mendía, M., Lara Arias, J., Álvarez Lozano, E., Said Fernández, S., Soto Domínguez, A., Padilla Rivas, G. R., Martínez Rodríguez, H. G.
Format:	Article
Language:	English
Published:	Asociación Brasileña de Divulgación Científica 2015
Online Access:	http://eprints.uanl.mx/29808/1/29808.pdf