WT1 silencing by RNAi synergizes with chemotherapeutic agents and induces chemosensitization to doxorubicin and cisplatin in B16F10 murine melanoma cells
The Wilm's tumor gene (WT1), encoding a transcription factor that modulates the expression of certain genes that are involved in proliferation and apoptosis, is overexpressed in numerous solid tumors. WT1 is important for cell proliferation and in the diagnosis of melanoma. The objectives of th...
| Autores principales: | , , , , , , , |
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| Formato: | Artículo |
| Lenguaje: | English |
| Publicado: |
Spandidos Publications
2012
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| Materias: | |
| Acceso en línea: | http://eprints.uanl.mx/28044/1/662.pdf |