Salivary rheumatoid factor in primary and secondary Sjögren’s syndrome

Sjögren's syndrome is a chronic autoimmune disease, characterized by the presence of hyposalivation and xerophthalmia, which in addition to other factors is diagnosed by the presence of rheumatoid factor in blood. The objective of the present study is to evaluate the presence of rheumatoid fact...

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Autores principales: Triana Reyes, Silvia Arely, Martínez Sandoval, Gloria, Rodríguez Franco, Norma Idalia, Chapa Arizpe, María Gabriela, Rodríguez Pulido, Jesús Israel, Alcázar Pizaña, Andrea Guadalupe, Riega Torres, Janett Carmen Luzmila
Formato: Artículo
Lenguaje:inglés
Publicado: Universidad de Concepción 2019
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Acceso en línea:http://eprints.uanl.mx/24819/1/24819.pdf
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author Triana Reyes, Silvia Arely
Martínez Sandoval, Gloria
Rodríguez Franco, Norma Idalia
Chapa Arizpe, María Gabriela
Rodríguez Pulido, Jesús Israel
Alcázar Pizaña, Andrea Guadalupe
Riega Torres, Janett Carmen Luzmila
author_facet Triana Reyes, Silvia Arely
Martínez Sandoval, Gloria
Rodríguez Franco, Norma Idalia
Chapa Arizpe, María Gabriela
Rodríguez Pulido, Jesús Israel
Alcázar Pizaña, Andrea Guadalupe
Riega Torres, Janett Carmen Luzmila
author_sort Triana Reyes, Silvia Arely
collection Repositorio Institucional
description Sjögren's syndrome is a chronic autoimmune disease, characterized by the presence of hyposalivation and xerophthalmia, which in addition to other factors is diagnosed by the presence of rheumatoid factor in blood. The objective of the present study is to evaluate the presence of rheumatoid factor (IgG-IgM) in the saliva of patients with primary and secondary Sjögren's syndrome. Materials and methods: Forty samples from patients with primary and secondary Sjögren's syndrome previously diagnosed by the Arthritis and Rheumatism Specialist Center of the Autonomous University of Nuevo Leon were analyzed. Samples were taken from the saliva using the Carlson-Crittenden device to evaluate the IgG-IgM immunocomplex using the ELISA method. Results: No significant difference was found between the presence of IgM in primary (0.099±0.016) and secondary Sjögren syndrome (0.098±0.017), however, a high presence of IgG was found in the group of patients with secondary Sjögren's syndrome (0.134±0.054). Conclusion: The search for diagnostic tools using salivary biomarkers has come with economic and clinical advantages, however, in the present study no significant changes were found in salivary rheumatoid factor between both groups.
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spelling eprints-248192023-05-18T18:38:07Z http://eprints.uanl.mx/24819/ Salivary rheumatoid factor in primary and secondary Sjögren’s syndrome Triana Reyes, Silvia Arely Martínez Sandoval, Gloria Rodríguez Franco, Norma Idalia Chapa Arizpe, María Gabriela Rodríguez Pulido, Jesús Israel Alcázar Pizaña, Andrea Guadalupe Riega Torres, Janett Carmen Luzmila RC Medicina Interna, Psiquiatría, Neurología Sjögren's syndrome is a chronic autoimmune disease, characterized by the presence of hyposalivation and xerophthalmia, which in addition to other factors is diagnosed by the presence of rheumatoid factor in blood. The objective of the present study is to evaluate the presence of rheumatoid factor (IgG-IgM) in the saliva of patients with primary and secondary Sjögren's syndrome. Materials and methods: Forty samples from patients with primary and secondary Sjögren's syndrome previously diagnosed by the Arthritis and Rheumatism Specialist Center of the Autonomous University of Nuevo Leon were analyzed. Samples were taken from the saliva using the Carlson-Crittenden device to evaluate the IgG-IgM immunocomplex using the ELISA method. Results: No significant difference was found between the presence of IgM in primary (0.099±0.016) and secondary Sjögren syndrome (0.098±0.017), however, a high presence of IgG was found in the group of patients with secondary Sjögren's syndrome (0.134±0.054). Conclusion: The search for diagnostic tools using salivary biomarkers has come with economic and clinical advantages, however, in the present study no significant changes were found in salivary rheumatoid factor between both groups. Universidad de Concepción 2019 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/24819/1/24819.pdf http://eprints.uanl.mx/24819/1.haspreviewThumbnailVersion/24819.pdf Triana Reyes, Silvia Arely y Martínez Sandoval, Gloria y Rodríguez Franco, Norma Idalia y Chapa Arizpe, María Gabriela y Rodríguez Pulido, Jesús Israel y Alcázar Pizaña, Andrea Guadalupe y Riega Torres, Janett Carmen Luzmila (2019) Salivary rheumatoid factor in primary and secondary Sjögren’s syndrome. Journal Of Oral Research, 8 (3). pp. 196-200. ISSN 07192460 https://doi.org/10.17126/joralres.2019.030
spellingShingle RC Medicina Interna, Psiquiatría, Neurología
Triana Reyes, Silvia Arely
Martínez Sandoval, Gloria
Rodríguez Franco, Norma Idalia
Chapa Arizpe, María Gabriela
Rodríguez Pulido, Jesús Israel
Alcázar Pizaña, Andrea Guadalupe
Riega Torres, Janett Carmen Luzmila
Salivary rheumatoid factor in primary and secondary Sjögren’s syndrome
thumbnail https://rediab.uanl.mx/themes/sandal5/images/online.png
title Salivary rheumatoid factor in primary and secondary Sjögren’s syndrome
title_full Salivary rheumatoid factor in primary and secondary Sjögren’s syndrome
title_fullStr Salivary rheumatoid factor in primary and secondary Sjögren’s syndrome
title_full_unstemmed Salivary rheumatoid factor in primary and secondary Sjögren’s syndrome
title_short Salivary rheumatoid factor in primary and secondary Sjögren’s syndrome
title_sort salivary rheumatoid factor in primary and secondary sjogren s syndrome
topic RC Medicina Interna, Psiquiatría, Neurología
url http://eprints.uanl.mx/24819/1/24819.pdf
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