Pegylated interferon-α2b and ribavirin decrease claudin-1 and E-cadherin expression in HepG2 and Huh-7.5 cells

Background. Hepatitis C virus (HCV) infection usually results in long-term viremia. Entry of HCV into the he-patocyte requires claudin-1, -6, -9 and occludin. The efficacy of Pegylated interferon-α (PEG-IFN) treatment against HCV infection increased when ribavirin (RBV) was added to the therapeutic...

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Bibliographic Details

Main Authors:	Rendón Huerta, Erika P., Torres Martínez, Ana, Charles Niño, Claudia, Rivas Estilla, Ana María, Páez, A., Fortoul, Teresa I., Montaño, Luis F.
Format:	Article
Language:	English
Published:	2013
Subjects:	RC Medicina Interna, Psiquiatría, Neurología
Online Access:	http://eprints.uanl.mx/23504/1/23504.pdf