Pegylated interferon-α2b and ribavirin decrease claudin-1 and E-cadherin expression in HepG2 and Huh-7.5 cells
Background. Hepatitis C virus (HCV) infection usually results in long-term viremia. Entry of HCV into the he-patocyte requires claudin-1, -6, -9 and occludin. The efficacy of Pegylated interferon-α (PEG-IFN) treatment against HCV infection increased when ribavirin (RBV) was added to the therapeutic...
Autores principales: | , , , , , , |
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Formato: | Artículo |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | http://eprints.uanl.mx/23504/1/23504.pdf |