Azathioprine: its uses in dermatology

This is a narrative review of azathioprine. This medication is immunomodulatory and immunosuppressive, and it has been used widely through different medical specialties to modify disease. It has been proven useful for several dermatoses and it has encountered success when used as an off-label ind...

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Autores principales: Chávez Álvarez, Sonia, Ocampo Candiani, Jorge, Gómez Flores, Minerva, Villarreal Martínez, Alejandra, Herz Ruelas, Maira Elizabeth, Garza Garza, Rubicela
Formato: Artículo
Lenguaje:inglés
Publicado: 2020
Materias:
Acceso en línea:http://eprints.uanl.mx/20089/1/1-s2.0-S0365059620302191-main.pdf
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author Chávez Álvarez, Sonia
Ocampo Candiani, Jorge
Gómez Flores, Minerva
Villarreal Martínez, Alejandra
Herz Ruelas, Maira Elizabeth
Garza Garza, Rubicela
author_facet Chávez Álvarez, Sonia
Ocampo Candiani, Jorge
Gómez Flores, Minerva
Villarreal Martínez, Alejandra
Herz Ruelas, Maira Elizabeth
Garza Garza, Rubicela
author_sort Chávez Álvarez, Sonia
collection Repositorio Institucional
description This is a narrative review of azathioprine. This medication is immunomodulatory and immunosuppressive, and it has been used widely through different medical specialties to modify disease. It has been proven useful for several dermatoses and it has encountered success when used as an off-label indication for other dermatologic diseases. Its mechanism of action is described thoroughly, as well as precautions for monitoring adequate levels in patients using it. Dermatologists should also be aware of the possible adverse events it may present. In dermatology it can be used in bullous and autoimmune diseases, and in other conditions, including intractable pruritus, atopic dermatitis, photodermatoses, psoriasis, and others. Azathioprine offers an alternative as a steroid-sparing agent and this review helps dermatologists prescribe it safely to all patients who require it.
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spelling eprints-200892020-10-14T17:46:48Z http://eprints.uanl.mx/20089/ Azathioprine: its uses in dermatology Chávez Álvarez, Sonia Ocampo Candiani, Jorge Gómez Flores, Minerva Villarreal Martínez, Alejandra Herz Ruelas, Maira Elizabeth Garza Garza, Rubicela RL Dermatología This is a narrative review of azathioprine. This medication is immunomodulatory and immunosuppressive, and it has been used widely through different medical specialties to modify disease. It has been proven useful for several dermatoses and it has encountered success when used as an off-label indication for other dermatologic diseases. Its mechanism of action is described thoroughly, as well as precautions for monitoring adequate levels in patients using it. Dermatologists should also be aware of the possible adverse events it may present. In dermatology it can be used in bullous and autoimmune diseases, and in other conditions, including intractable pruritus, atopic dermatitis, photodermatoses, psoriasis, and others. Azathioprine offers an alternative as a steroid-sparing agent and this review helps dermatologists prescribe it safely to all patients who require it. 2020 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/20089/1/1-s2.0-S0365059620302191-main.pdf http://eprints.uanl.mx/20089/1.haspreviewThumbnailVersion/1-s2.0-S0365059620302191-main.pdf Chávez Álvarez, Sonia y Ocampo Candiani, Jorge y Gómez Flores, Minerva y Villarreal Martínez, Alejandra y Herz Ruelas, Maira Elizabeth y Garza Garza, Rubicela (2020) Azathioprine: its uses in dermatology. Anais Brasileiros de Dermatologia. ISSN 0365-0596 (Por publicarse) http://doi.org/10.1016/j.abd.2020.05.003 doi:10.1016/j.abd.2020.05.003
spellingShingle RL Dermatología
Chávez Álvarez, Sonia
Ocampo Candiani, Jorge
Gómez Flores, Minerva
Villarreal Martínez, Alejandra
Herz Ruelas, Maira Elizabeth
Garza Garza, Rubicela
Azathioprine: its uses in dermatology
thumbnail https://rediab.uanl.mx/themes/sandal5/images/online.png
title Azathioprine: its uses in dermatology
title_full Azathioprine: its uses in dermatology
title_fullStr Azathioprine: its uses in dermatology
title_full_unstemmed Azathioprine: its uses in dermatology
title_short Azathioprine: its uses in dermatology
title_sort azathioprine its uses in dermatology
topic RL Dermatología
url http://eprints.uanl.mx/20089/1/1-s2.0-S0365059620302191-main.pdf
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