| Summary: | This is a narrative review of azathioprine. This medication is immunomodulatory and
immunosuppressive, and it has been used widely through different medical specialties to modify
disease. It has been proven useful for several dermatoses and it has encountered success
when used as an off-label indication for other dermatologic diseases. Its mechanism of action
is described thoroughly, as well as precautions for monitoring adequate levels in patients using
it. Dermatologists should also be aware of the possible adverse events it may present. In dermatology
it can be used in bullous and autoimmune diseases, and in other conditions, including
intractable pruritus, atopic dermatitis, photodermatoses, psoriasis, and others. Azathioprine
offers an alternative as a steroid-sparing agent and this review helps dermatologists prescribe
it safely to all patients who require it.
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