Ectopic BAT mUCP-1 overexpression in SKM by delivering a BMP7/PRDM16/PGC-1a gene cocktail or single PRMD16 using non-viral UTMD gene therapy.

Here we present our progress in inducing an ectopic brown adipose tissue (BAT) phenotype in skeletal muscle (SKM) as a potential gene therapy for obesity and its comorbidities. We used ultrasound-targeted microbubble destruction (UTMD), a novel targeted, non-viral approach to gene therapy, to delive...

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Detalles Bibliográficos
Autores principales:	Chen, Shuyuan, Bastarrachea, Raúl A., Shen, Jin Song, Laviada Nagel, Antonio, Rodríguez Ayala, Ernesto, Nava González, Edna Judith, Huang, Pintong, DeFronzo, Ralph A., Kent, Jack W., Grayburn, Paul A.
Formato:	Artículo
Lenguaje:	inglés
Publicado:	2018
Materias:	R Medicina en General
Acceso en línea:	http://eprints.uanl.mx/18915/1/30072816

Ectopic BAT mUCP-1 overexpression in SKM by delivering a BMP7/PRDM16/PGC-1a gene cocktail or single PRMD16 using non-viral UTMD gene therapy por Chen, Shuyuan, Bastarrachea, Raúl A., Shen, Jin Song, Laviada Nagel, Antonio, Rodríguez Ayala, Ernesto, Nava González, Edna Judith, Huang, Pintong, DeFronzo, Ralph A., Kent, Jack W., Grayburn, Paul A.

Publicado 2018

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Artículo

Ectopic BAT mUCP-1 overexpression in SKM by delivering a BMP7/PRDM16/PGC-1a gene cocktail or single PRMD16 using non-viral UTMD gene therapy.

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