Quantitative Aspect of Leucophyllum frutescens Fraction before and after Encapsulation in Polymeric Nanoparticles

The interest on plants has been focalized due to their biological activities. Extracts or fractions from plants in biodegradable polymeric nanoparticles (NP) provide many advantages on application studies. The encapsulation of the extract or fraction in NP is determined for the establishment of th...

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Bibliographic Details
Main Authors: Martínez Rivas, Claudia Janeth, Alvarez Román, Rocío, Rivas Morales, Catalina, Elaissari, Abdelhamid, Fessi, Hatem, Galindo Rodríguez, Sergio Arturo
Format: Article
Language:English
Published: 2017
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Online Access:http://eprints.uanl.mx/18235/1/527.pdf
Description
Summary:The interest on plants has been focalized due to their biological activities. Extracts or fractions from plants in biodegradable polymeric nanoparticles (NP) provide many advantages on application studies. The encapsulation of the extract or fraction in NP is determined for the establishment of the test dose. HPLC method is an alternative to calculate this parameter. An analytical method based on HPLC for quantification of a hexane fraction from L. frutescens was developed and validated according to ICH. Different concentrations of the hexane fraction from leaves (HFL) were prepared (100–600