Macrophages Facilitate Resistance to Anti-VEGF Therapy by Altered VEGFR Expression

Macrophages Facilitate Resistance to Anti-VEGF Therapy by Altered VEGFR Expression

Abstract Purpose: VEGF-targeted therapies have modest efficacy in cancerpatients, butacquiredresistance iscommon. Themechanisms underlying such resistance are poorly understood. Experimental Design: To evaluate the potential role of immune cells in the development of resistance to VEGF blockade, we...

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Detalles Bibliográficos
Autores principales: Dalton, Heather J., Pradeep, Sunila, McGuire, Michael, Hailemichael, Yared, MA, Shaolin, Lyons, Yasmin, Armaiz Pena, Guillermo N., Previs, Rebecca A., Hansen, Jean Marie, Rupaimoole, Rajesha, González Villasana, Vianey, Cho, Min Soon, Wu, Sherry Y., Mangala, Lingegowda S., Jennings, Nicholas B., Hu, Wei, Langley, Robert, Mu, Hong, Andreeff, Michael, Bar Eli, Menashe, Overwijk, Willem, Ram, Prahlad, Lopez Berestein, Gabriel, Coleman, Robert L., Sood, Anil K.
Formato: Artículo
Lenguaje:English
Publicado: 2017
Acceso en línea:http://eprints.uanl.mx/17479/1/308.pdf

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