Maternal overnutrition by hypercaloric diets programs hypothalamic mitochondrial fusion and metabolic dysfunction in rat male offspring

Abstract Background: Maternal overnutrition including pre-pregnancy, pregnancy and lactation promotes a lipotoxic insult leading to metabolic dysfunction in offspring. Diet-induced obesity models (DIO) show that changes in hypothalamic mitochondria fusion and fission dynamics modulate metabolic dysf...

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Main Authors:	Cárdenas Pérez, Robbi Elizabeth, Fuentes Mera, Lizeth, De la Garza, Ana Laura, Torre Villalvazo, Iván, Reyes Castro, Luis A., Rodríguez Rocha, Humberto, García García, Aracely, Corona Castillo, Juan Carlos, Tovar, Armando R., Zambrano, Elena, Ortiz López, Rocío, Saville, Jennifer, Fuller, Maria, Camacho Morales, Alberto
Format:	Article
Language:	English
Published:	BioMed Central 2018
Subjects:	QP Fisiología
Online Access:	http://eprints.uanl.mx/16206/1/120.pdf