Maternal overnutrition by hypercaloric diets programs hypothalamic mitochondrial fusion and metabolic dysfunction in rat male offspring

Abstract Background: Maternal overnutrition including pre-pregnancy, pregnancy and lactation promotes a lipotoxic insult leading to metabolic dysfunction in offspring. Diet-induced obesity models (DIO) show that changes in hypothalamic mitochondria fusion and fission dynamics modulate metabolic dysf...

Descripción completa

Detalles Bibliográficos
Autores principales: Cárdenas Pérez, Robbi Elizabeth, Fuentes Mera, Lizeth, De la Garza, Ana Laura, Torre Villalvazo, Iván, Reyes Castro, Luis A., Rodríguez Rocha, Humberto, García García, Aracely, Corona Castillo, Juan Carlos, Tovar, Armando R., Zambrano, Elena, Ortiz López, Rocío, Saville, Jennifer, Fuller, Maria, Camacho Morales, Alberto
Formato: Artículo
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:http://eprints.uanl.mx/16206/1/120.pdf