A DNA Vaccine Encoding SA-4-1BBL Fused to HPV-16 E7 Antigen Has Prophylactic and Therapeutic Efficacy in a Cervical Cancer Mouse Model

TheSA-4-1BBL,anoligomericnovelformofthenaturalligandforthe4-1BBco-stimulatory receptorofthetumornecrosisfactor(TNF)superfamily,asarecombinantproteinhaspotentpleiotropic effects on cells of innate, adaptive, and regulatory immunity with demonstrated therapeutic efficacy in several tumor models. However,...

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Bibliographic Details

Main Authors:	Garza Morales, Rodolfo, Pérez Trujillo, José Juan, Martínez Jaramillo, Elvis, Saucedo Cárdenas, Odila, Loera Arias, María de Jesús, García García, Aracely, Rodríguez Rocha, Humberto, Yolcu, Esma, Shirwan, Haval, Gomez Gutierrez, Jorge G, Montes de Oca Luna, Roberto
Format:	Article
Language:	English
Published:	2019
Online Access:	http://eprints.uanl.mx/15817/1/19.pdf