The mycetoma knowledge gap: identification of research priorities
Mycetoma is a tropical disease which is caused by a taxonomically diverse range of actinomycetes (actinomycetoma) and fungi (eumycetoma). The disease was only recently listed by the World Health Organization (WHO) as a neglected tropical disease (NTD). This recognition is the direct result of a mee...
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Format: | Article |
Language: | English |
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Public Library of Science
2014
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Online Access: | http://eprints.uanl.mx/15246/1/353.PDF |
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author | Wanke, Bodo Van de Sande, Wendy W. J. Maghoub, El Sheikh Fahal, Ahmed Hassan Goodfellow, Michael Welsh Lozano, Oliverio Zijlstra, Ed E. |
author_facet | Wanke, Bodo Van de Sande, Wendy W. J. Maghoub, El Sheikh Fahal, Ahmed Hassan Goodfellow, Michael Welsh Lozano, Oliverio Zijlstra, Ed E. |
author_sort | Wanke, Bodo |
collection | Repositorio Institucional |
description | Mycetoma is a tropical disease which is caused by a
taxonomically diverse range of actinomycetes (actinomycetoma) and fungi (eumycetoma). The disease was only recently listed by the World Health Organization (WHO) as a neglected tropical disease (NTD). This recognition is the direct result of a meeting held in Geneva on February 1, 2013, in which experts on the disease from around the world met to identify the key research priorities needed to combat mycetoma. The areas that need to be addressed are highlighted here. The initial priority is to establish the incidence and prevalence of the disease in regions where mycetoma is endemic, prior to determining the primary reservoirs of the predominant causal agents and their mode of transmission to susceptible individuals in order to
establish novel interventions that will reduce the impact of the disease on individuals, families, and communities.
Critically, economical, reliable, and effective methods are required to achieve early diagnosis of infections and
consequential improved therapeutic outcomes. Molecular
techniques and serological assays were considered the most promising in the development of novel diagnostic tools to be used in endemic settings. Improved strategies for treating eumycetoma and actinomycetoma are also considered. |
format | Article |
id | eprints-15246 |
institution | UANL |
language | English |
publishDate | 2014 |
publisher | Public Library of Science |
record_format | eprints |
spelling | eprints-152462021-07-20T14:30:55Z http://eprints.uanl.mx/15246/ The mycetoma knowledge gap: identification of research priorities Wanke, Bodo Van de Sande, Wendy W. J. Maghoub, El Sheikh Fahal, Ahmed Hassan Goodfellow, Michael Welsh Lozano, Oliverio Zijlstra, Ed E. RC Medicina Interna, Psiquiatría, Neurología Mycetoma is a tropical disease which is caused by a taxonomically diverse range of actinomycetes (actinomycetoma) and fungi (eumycetoma). The disease was only recently listed by the World Health Organization (WHO) as a neglected tropical disease (NTD). This recognition is the direct result of a meeting held in Geneva on February 1, 2013, in which experts on the disease from around the world met to identify the key research priorities needed to combat mycetoma. The areas that need to be addressed are highlighted here. The initial priority is to establish the incidence and prevalence of the disease in regions where mycetoma is endemic, prior to determining the primary reservoirs of the predominant causal agents and their mode of transmission to susceptible individuals in order to establish novel interventions that will reduce the impact of the disease on individuals, families, and communities. Critically, economical, reliable, and effective methods are required to achieve early diagnosis of infections and consequential improved therapeutic outcomes. Molecular techniques and serological assays were considered the most promising in the development of novel diagnostic tools to be used in endemic settings. Improved strategies for treating eumycetoma and actinomycetoma are also considered. Public Library of Science 2014 Article PeerReviewed other en cc_by_nc_nd http://eprints.uanl.mx/15246/1/353.PDF http://eprints.uanl.mx/15246/1.haspreviewThumbnailVersion/353.PDF Wanke, Bodo y Van de Sande, Wendy W. J. y Maghoub, El Sheikh y Fahal, Ahmed Hassan y Goodfellow, Michael y Welsh Lozano, Oliverio y Zijlstra, Ed E. (2014) The mycetoma knowledge gap: identification of research priorities. PloS Neglected tropical diseases, 8 (3). e2667. ISSN 1935-2727 http://doi.org/10.1371/journal.pntd.0002667 doi:10.1371/journal.pntd.0002667 |
spellingShingle | RC Medicina Interna, Psiquiatría, Neurología Wanke, Bodo Van de Sande, Wendy W. J. Maghoub, El Sheikh Fahal, Ahmed Hassan Goodfellow, Michael Welsh Lozano, Oliverio Zijlstra, Ed E. The mycetoma knowledge gap: identification of research priorities |
thumbnail | https://rediab.uanl.mx/themes/sandal5/images/online.png |
title | The mycetoma knowledge gap: identification of research priorities |
title_full | The mycetoma knowledge gap: identification of research priorities |
title_fullStr | The mycetoma knowledge gap: identification of research priorities |
title_full_unstemmed | The mycetoma knowledge gap: identification of research priorities |
title_short | The mycetoma knowledge gap: identification of research priorities |
title_sort | mycetoma knowledge gap identification of research priorities |
topic | RC Medicina Interna, Psiquiatría, Neurología |
url | http://eprints.uanl.mx/15246/1/353.PDF |
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