Clinical features and outcome of mucormycosis
Mucormycosis (MCM) is a life-threatening infection that carries high mortality rates despite recent advances in its diagnosis and treatment. The objective was to report 14 cases of mucormycosis infection and review the relevant literature. We retrospectively analyzed the demographic and clinical dat...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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2014
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| Online Access: | http://eprints.uanl.mx/15221/1/315.pdf |
| _version_ | 1824414288675078144 |
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| author | Camara Lemarroy, Carlos Rodrigo González Moreno, Emmanuel Irineo Rodríguez Gutiérrez, René Rendón Ramírez, Erick Joel Ayala Cortés, Ana Sofía Fraga Hernández, Martha Lizeth García Labastida, Laura Elvira Galarza Delgado, Dionicio Ángel |
| author_facet | Camara Lemarroy, Carlos Rodrigo González Moreno, Emmanuel Irineo Rodríguez Gutiérrez, René Rendón Ramírez, Erick Joel Ayala Cortés, Ana Sofía Fraga Hernández, Martha Lizeth García Labastida, Laura Elvira Galarza Delgado, Dionicio Ángel |
| author_sort | Camara Lemarroy, Carlos Rodrigo |
| collection | Repositorio Institucional |
| description | Mucormycosis (MCM) is a life-threatening infection that carries high mortality rates despite recent advances in its diagnosis and treatment. The objective was to report 14 cases of mucormycosis infection and review the relevant literature. We retrospectively analyzed the demographic and clinical data of 14 consecutive patients that presented with MCM in a tertiary-care teaching hospital in northern Mexico. The mean age of the patients was 39.9 (range 5–65). Nine of the patients were male. Ten patients had diabetes mellitus as the underlying disease, and 6 patients had a hematological malignancy (acute leukemia). Of the diabetic patients, 3 had chronic renal failure and 4 presented with diabetic ketoacidosis. All patients had rhinocerebral involvement. In-hospital mortality was 50%. All patients received medical therapy with polyene antifungals and 11 patients underwent surgical therapy. Survivors were significantly younger and less likely to have diabetes than nonsurvivors, and had higher levels of serum albumin on admission. The clinical outcome of patients with MCM is poor. Uncontrolled diabetes and age are negative prognostic factors. |
| format | Article |
| id | eprints-15221 |
| institution | UANL |
| language | English |
| publishDate | 2014 |
| record_format | eprints |
| spelling | eprints-152212024-12-09T21:11:41Z http://eprints.uanl.mx/15221/ Clinical features and outcome of mucormycosis Camara Lemarroy, Carlos Rodrigo González Moreno, Emmanuel Irineo Rodríguez Gutiérrez, René Rendón Ramírez, Erick Joel Ayala Cortés, Ana Sofía Fraga Hernández, Martha Lizeth García Labastida, Laura Elvira Galarza Delgado, Dionicio Ángel QR Microbiología RC Medicina Interna, Psiquiatría, Neurología Mucormycosis (MCM) is a life-threatening infection that carries high mortality rates despite recent advances in its diagnosis and treatment. The objective was to report 14 cases of mucormycosis infection and review the relevant literature. We retrospectively analyzed the demographic and clinical data of 14 consecutive patients that presented with MCM in a tertiary-care teaching hospital in northern Mexico. The mean age of the patients was 39.9 (range 5–65). Nine of the patients were male. Ten patients had diabetes mellitus as the underlying disease, and 6 patients had a hematological malignancy (acute leukemia). Of the diabetic patients, 3 had chronic renal failure and 4 presented with diabetic ketoacidosis. All patients had rhinocerebral involvement. In-hospital mortality was 50%. All patients received medical therapy with polyene antifungals and 11 patients underwent surgical therapy. Survivors were significantly younger and less likely to have diabetes than nonsurvivors, and had higher levels of serum albumin on admission. The clinical outcome of patients with MCM is poor. Uncontrolled diabetes and age are negative prognostic factors. 2014 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/15221/1/315.pdf http://eprints.uanl.mx/15221/1.haspreviewThumbnailVersion/315.pdf Camara Lemarroy, Carlos Rodrigo y González Moreno, Emmanuel Irineo y Rodríguez Gutiérrez, René y Rendón Ramírez, Erick Joel y Ayala Cortés, Ana Sofía y Fraga Hernández, Martha Lizeth y García Labastida, Laura Elvira y Galarza Delgado, Dionicio Ángel (2014) Clinical features and outcome of mucormycosis. Interdisciplinary Perspectives on Infectious Diseases, 2014. pp. 1-5. ISSN 1687-708X http://doi.org/10.1155/2014/562610 doi:10.1155/2014/562610 |
| spellingShingle | QR Microbiología RC Medicina Interna, Psiquiatría, Neurología Camara Lemarroy, Carlos Rodrigo González Moreno, Emmanuel Irineo Rodríguez Gutiérrez, René Rendón Ramírez, Erick Joel Ayala Cortés, Ana Sofía Fraga Hernández, Martha Lizeth García Labastida, Laura Elvira Galarza Delgado, Dionicio Ángel Clinical features and outcome of mucormycosis |
| thumbnail | https://rediab.uanl.mx/themes/sandal5/images/online.png |
| title | Clinical features and outcome of mucormycosis |
| title_full | Clinical features and outcome of mucormycosis |
| title_fullStr | Clinical features and outcome of mucormycosis |
| title_full_unstemmed | Clinical features and outcome of mucormycosis |
| title_short | Clinical features and outcome of mucormycosis |
| title_sort | clinical features and outcome of mucormycosis |
| topic | QR Microbiología RC Medicina Interna, Psiquiatría, Neurología |
| url | http://eprints.uanl.mx/15221/1/315.pdf |
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