Neurofilamentopathy in Neurodegenerative Diseases
Neurofilament protein alterations are found in many neurodegenerative diseases, such as amyotrophic lateral sclerosis, Parkinson, Alzheimer, and Charcot-Marie-Tooth. Abnormal modifications of neurofilament, such as mutation, oxidation and phosphorylation, are linked to the disease-related alteration...
Autores principales: | , , , , , , |
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Formato: | Artículo |
Lenguaje: | inglés |
Publicado: |
2011
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Materias: | |
Acceso en línea: | http://eprints.uanl.mx/15057/1/677.pdf |
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author | Liu, Quan Xie, Fang Alvarado Diaz, Abdiel Smith, Mark A. Moreira, Paula I. Zhu, Xiongwei Perry, George |
author_facet | Liu, Quan Xie, Fang Alvarado Diaz, Abdiel Smith, Mark A. Moreira, Paula I. Zhu, Xiongwei Perry, George |
author_sort | Liu, Quan |
collection | Repositorio Institucional |
description | Neurofilament protein alterations are found in many neurodegenerative diseases, such as amyotrophic lateral sclerosis, Parkinson, Alzheimer, and Charcot-Marie-Tooth. Abnormal modifications of neurofilament, such as mutation, oxidation and phosphorylation, are linked to the disease-related alteration. In this review, the most recent discovery and central arguments about functions, pathological modifications, and genetic mutations related to neurofilaments in neurodegenerative diseases is presented. |
format | Article |
id | eprints-15057 |
institution | UANL |
language | English |
publishDate | 2011 |
record_format | eprints |
spelling | eprints-150572019-05-07T21:12:10Z http://eprints.uanl.mx/15057/ Neurofilamentopathy in Neurodegenerative Diseases Liu, Quan Xie, Fang Alvarado Diaz, Abdiel Smith, Mark A. Moreira, Paula I. Zhu, Xiongwei Perry, George RC Medicina Interna, Psiquiatría, Neurología Neurofilament protein alterations are found in many neurodegenerative diseases, such as amyotrophic lateral sclerosis, Parkinson, Alzheimer, and Charcot-Marie-Tooth. Abnormal modifications of neurofilament, such as mutation, oxidation and phosphorylation, are linked to the disease-related alteration. In this review, the most recent discovery and central arguments about functions, pathological modifications, and genetic mutations related to neurofilaments in neurodegenerative diseases is presented. 2011 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/15057/1/677.pdf http://eprints.uanl.mx/15057/1.haspreviewThumbnailVersion/677.pdf Liu, Quan y Xie, Fang y Alvarado Diaz, Abdiel y Smith, Mark A. y Moreira, Paula I. y Zhu, Xiongwei y Perry, George (2011) Neurofilamentopathy in Neurodegenerative Diseases. The Open Neurology Journal, 5 (1). pp. 58-62. ISSN 1874205X http://doi.org/10.2174/1874205X01105010058 doi:10.2174/1874205X01105010058 |
spellingShingle | RC Medicina Interna, Psiquiatría, Neurología Liu, Quan Xie, Fang Alvarado Diaz, Abdiel Smith, Mark A. Moreira, Paula I. Zhu, Xiongwei Perry, George Neurofilamentopathy in Neurodegenerative Diseases |
thumbnail | https://rediab.uanl.mx/themes/sandal5/images/online.png |
title | Neurofilamentopathy in Neurodegenerative Diseases |
title_full | Neurofilamentopathy in Neurodegenerative Diseases |
title_fullStr | Neurofilamentopathy in Neurodegenerative Diseases |
title_full_unstemmed | Neurofilamentopathy in Neurodegenerative Diseases |
title_short | Neurofilamentopathy in Neurodegenerative Diseases |
title_sort | neurofilamentopathy in neurodegenerative diseases |
topic | RC Medicina Interna, Psiquiatría, Neurología |
url | http://eprints.uanl.mx/15057/1/677.pdf |
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