Neurofilamentopathy in Neurodegenerative Diseases

Neurofilament protein alterations are found in many neurodegenerative diseases, such as amyotrophic lateral sclerosis, Parkinson, Alzheimer, and Charcot-Marie-Tooth. Abnormal modifications of neurofilament, such as mutation, oxidation and phosphorylation, are linked to the disease-related alteration...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Quan, Xie, Fang, Alvarado Diaz, Abdiel, Smith, Mark A., Moreira, Paula I., Zhu, Xiongwei, Perry, George
Formato: Artículo
Lenguaje:inglés
Publicado: 2011
Materias:
Acceso en línea:http://eprints.uanl.mx/15057/1/677.pdf
_version_ 1824414241462943744
author Liu, Quan
Xie, Fang
Alvarado Diaz, Abdiel
Smith, Mark A.
Moreira, Paula I.
Zhu, Xiongwei
Perry, George
author_facet Liu, Quan
Xie, Fang
Alvarado Diaz, Abdiel
Smith, Mark A.
Moreira, Paula I.
Zhu, Xiongwei
Perry, George
author_sort Liu, Quan
collection Repositorio Institucional
description Neurofilament protein alterations are found in many neurodegenerative diseases, such as amyotrophic lateral sclerosis, Parkinson, Alzheimer, and Charcot-Marie-Tooth. Abnormal modifications of neurofilament, such as mutation, oxidation and phosphorylation, are linked to the disease-related alteration. In this review, the most recent discovery and central arguments about functions, pathological modifications, and genetic mutations related to neurofilaments in neurodegenerative diseases is presented.
format Article
id eprints-15057
institution UANL
language English
publishDate 2011
record_format eprints
spelling eprints-150572019-05-07T21:12:10Z http://eprints.uanl.mx/15057/ Neurofilamentopathy in Neurodegenerative Diseases Liu, Quan Xie, Fang Alvarado Diaz, Abdiel Smith, Mark A. Moreira, Paula I. Zhu, Xiongwei Perry, George RC Medicina Interna, Psiquiatría, Neurología Neurofilament protein alterations are found in many neurodegenerative diseases, such as amyotrophic lateral sclerosis, Parkinson, Alzheimer, and Charcot-Marie-Tooth. Abnormal modifications of neurofilament, such as mutation, oxidation and phosphorylation, are linked to the disease-related alteration. In this review, the most recent discovery and central arguments about functions, pathological modifications, and genetic mutations related to neurofilaments in neurodegenerative diseases is presented. 2011 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/15057/1/677.pdf http://eprints.uanl.mx/15057/1.haspreviewThumbnailVersion/677.pdf Liu, Quan y Xie, Fang y Alvarado Diaz, Abdiel y Smith, Mark A. y Moreira, Paula I. y Zhu, Xiongwei y Perry, George (2011) Neurofilamentopathy in Neurodegenerative Diseases. The Open Neurology Journal, 5 (1). pp. 58-62. ISSN 1874205X http://doi.org/10.2174/1874205X01105010058 doi:10.2174/1874205X01105010058
spellingShingle RC Medicina Interna, Psiquiatría, Neurología
Liu, Quan
Xie, Fang
Alvarado Diaz, Abdiel
Smith, Mark A.
Moreira, Paula I.
Zhu, Xiongwei
Perry, George
Neurofilamentopathy in Neurodegenerative Diseases
thumbnail https://rediab.uanl.mx/themes/sandal5/images/online.png
title Neurofilamentopathy in Neurodegenerative Diseases
title_full Neurofilamentopathy in Neurodegenerative Diseases
title_fullStr Neurofilamentopathy in Neurodegenerative Diseases
title_full_unstemmed Neurofilamentopathy in Neurodegenerative Diseases
title_short Neurofilamentopathy in Neurodegenerative Diseases
title_sort neurofilamentopathy in neurodegenerative diseases
topic RC Medicina Interna, Psiquiatría, Neurología
url http://eprints.uanl.mx/15057/1/677.pdf
work_keys_str_mv AT liuquan neurofilamentopathyinneurodegenerativediseases
AT xiefang neurofilamentopathyinneurodegenerativediseases
AT alvaradodiazabdiel neurofilamentopathyinneurodegenerativediseases
AT smithmarka neurofilamentopathyinneurodegenerativediseases
AT moreirapaulai neurofilamentopathyinneurodegenerativediseases
AT zhuxiongwei neurofilamentopathyinneurodegenerativediseases
AT perrygeorge neurofilamentopathyinneurodegenerativediseases