Cutaneous graft-versus-host disease after hematopoietic stem cell transplant - a review
Graft-versus-host disease (GVHD) is a major complication of allogeneic hematopoietic stem cell transplants (allo-HSCT) associated with significant morbidity and mortality. The earliest and most common manifestation is cutaneous graft-versus-host disease. This review focuses on the pathophysiology, c...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
2016
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Subjects: | |
Online Access: | http://eprints.uanl.mx/14801/1/36.pdf |
Summary: | Graft-versus-host disease (GVHD) is a major complication of allogeneic hematopoietic stem cell transplants (allo-HSCT) associated with significant morbidity and mortality. The earliest and most common manifestation is cutaneous graft-versus-host disease. This review focuses on the pathophysiology, clinical features, prevention and treatment of cutaneous graft-versus-host disease. We discuss various insights into the disease’s mechanisms and the different treatments for acute and chronic skin graft-versus-host disease. |
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