Mild cognitive impairment
Abstract Mild Cognitive Impairment (MCI) is a disease between normal cognitive ageing and dementia. In recent years the term MCI has been recognized as a pre-dementia state, raising an important subject for investigation in the prevention of dementia. There are various terms related to pre-dementia...
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Formato: | Artículo |
Lenguaje: | inglés |
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UANL. Facultad de Medicina
2014
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Acceso en línea: | http://eprints.uanl.mx/11366/1/X1665579614283699_S300_en.pdf |
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author | Isordia Martínez, Javier Góngora Rivera, Juan Fernando Leal Bailey, H. Ortiz Jiménez, Xóchitl A. |
author_facet | Isordia Martínez, Javier Góngora Rivera, Juan Fernando Leal Bailey, H. Ortiz Jiménez, Xóchitl A. |
author_sort | Isordia Martínez, Javier |
collection | Repositorio Institucional |
description | Abstract Mild Cognitive Impairment (MCI) is a disease between normal cognitive ageing and dementia. In recent years the term MCI has been recognized as a pre-dementia state, raising an important subject for investigation in the prevention of dementia. There are various terms
related to pre-dementia MCI, such as isolated memory complaint and pre-Alzheimer’s disease; most of them do not comprise all the areas related to MCI. A central cholinergic deficit is present in amnestic MCI with neuronal loss in the Meynert basal nucleus. It is estimated that the rate of progression to dementia is about 10% every year. The prevalence of MCI is 10%-11% and the risk of progression to dementia is about 5%-16%. The continual development of pharmacologic approaches to modify and delay the natural history of progression of the disease motivates a great interest in an earlier diagnosis. |
format | Article |
id | eprints-11366 |
institution | UANL |
language | English |
publishDate | 2014 |
publisher | UANL. Facultad de Medicina |
record_format | eprints |
spelling | eprints-113662024-03-05T16:51:26Z http://eprints.uanl.mx/11366/ Mild cognitive impairment Isordia Martínez, Javier Góngora Rivera, Juan Fernando Leal Bailey, H. Ortiz Jiménez, Xóchitl A. RC Medicina Interna, Psiquiatría, Neurología Abstract Mild Cognitive Impairment (MCI) is a disease between normal cognitive ageing and dementia. In recent years the term MCI has been recognized as a pre-dementia state, raising an important subject for investigation in the prevention of dementia. There are various terms related to pre-dementia MCI, such as isolated memory complaint and pre-Alzheimer’s disease; most of them do not comprise all the areas related to MCI. A central cholinergic deficit is present in amnestic MCI with neuronal loss in the Meynert basal nucleus. It is estimated that the rate of progression to dementia is about 10% every year. The prevalence of MCI is 10%-11% and the risk of progression to dementia is about 5%-16%. The continual development of pharmacologic approaches to modify and delay the natural history of progression of the disease motivates a great interest in an earlier diagnosis. UANL. Facultad de Medicina 2014 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/11366/1/X1665579614283699_S300_en.pdf http://eprints.uanl.mx/11366/1.haspreviewThumbnailVersion/X1665579614283699_S300_en.pdf Isordia Martínez, Javier y Góngora Rivera, Juan Fernando y Leal Bailey, H. y Ortiz Jiménez, Xóchitl A. (2014) Mild cognitive impairment. Medicina universitaria, 16 (62). pp. 28-36. ISSN 1665-5796 |
spellingShingle | RC Medicina Interna, Psiquiatría, Neurología Isordia Martínez, Javier Góngora Rivera, Juan Fernando Leal Bailey, H. Ortiz Jiménez, Xóchitl A. Mild cognitive impairment |
thumbnail | https://rediab.uanl.mx/themes/sandal5/images/online.png |
title | Mild cognitive impairment |
title_full | Mild cognitive impairment |
title_fullStr | Mild cognitive impairment |
title_full_unstemmed | Mild cognitive impairment |
title_short | Mild cognitive impairment |
title_sort | mild cognitive impairment |
topic | RC Medicina Interna, Psiquiatría, Neurología |
url | http://eprints.uanl.mx/11366/1/X1665579614283699_S300_en.pdf |
work_keys_str_mv | AT isordiamartinezjavier mildcognitiveimpairment AT gongorariverajuanfernando mildcognitiveimpairment AT lealbaileyh mildcognitiveimpairment AT ortizjimenezxochitla mildcognitiveimpairment |