Search Results - thermogenic

Ectopic BAT mUCP-1 overexpression in SKM by delivering a BMP7/PRDM16/PGC-1a gene cocktail or single PRMD16 using non-viral UTMD gene therapy. by Chen, Shuyuan, Bastarrachea, Raúl A., Shen, Jin Song, Laviada Nagel, Antonio, Rodríguez Ayala, Ernesto, Nava González, Edna Judith, Huang, Pintong, DeFronzo, Ralph A., Kent, Jack W., Grayburn, Paul A.

“…We used ultrasound-targeted microbubble destruction (UTMD), a novel targeted, non-viral approach to gene therapy, to deliver genes in the BAT differentiation pathway into rodent SKM to engineer a thermogenic BAT phenotype with ectopic mUCP-1 overexpression. …”
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Ectopic BAT mUCP-1 overexpression in SKM by delivering a BMP7/PRDM16/PGC-1a gene cocktail or single PRMD16 using non-viral UTMD gene therapy by Chen, Shuyuan, Bastarrachea, Raúl A., Shen, Jin Song, Laviada Nagel, Antonio, Rodríguez Ayala, Ernesto, Nava González, Edna Judith, Huang, Pintong, DeFronzo, Ralph A., Kent, Jack W., Grayburn, Paul A.

“…We used ultrasound-targeted microbubble destruction (UTMD), a novel targeted, non-viral approach to gene therapy, to deliver genes in the BAT differentiation pathway into rodent SKM to engineer a thermogenic BAT phenotype with ectopic mUCP-1 overexpression. …”
Get full text