Resultados de búsqueda - gene expression

Evaluation of the TRPM2 channel as a biomarker in breast cancer using public databases analysis por Sumoza Toledo, Adriana, Espinoza Gabriel, Mario Iván, Montiel Condado, Dvorak

“…On the other hand, Kaplan-Meier analysis exhibited that low expression of TRPM2 could be used to predict poor outcome in ER- and HER2+ breast carcinoma patients. …”
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Triple negative breast cancer: Deciphering the biology and heterogeneity por Uscanga Perales, Grecia Iris, Santuario Facio, Sandra Karina, Ortiz López, Rocío

“…In this review, the literature search was done up to date on which gene expression profile of TNBC has been analyzed in order to identify the consensus on molecular mechanisms involved in carcinogenesis and/or the prognostic markers of the disease. …”
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Efecto de la temperatura en la respuesta inmune de Trichoplusia ni a bajas concentraciones de AcMNPV. por Orozco Flores, Alonso Alberto

“…Although at temperatures above 27°C, an increase of 334 times of the antiviral peptide gloverin expression was detected, this gene expression decreased 70% in larvae exposed to AcMNPV kept at 37°C. …”
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Efecto de la temperatura en la respuesta inmune de Trichoplusia ni a bajas concentraciones de AcMNPV. por Orozco Flores, Alonso Alberto

“…Although at temperatures above 27°C, an increase of 334 times of the antiviral peptide gloverin expression was detected, this gene expression decreased 70% in larvae exposed to AcMNPV kept at 37°C. …”
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Larval density mediates knockdown resistance to pyrethroid insecticides in adult Aedes aegypti por Grossman, Marissa K., Uc Puc, Valentín, Flores, Adriana E., Manrique Saide, Pablo C., Vazquez Prokopec, Gonzalo M.

“…Furthermore, phenotypic susceptibility to pyrethroids may be re-established in a resistant population through a gene x environment interaction, a finding that can lead to the development of novel resistance management strategies that capitalize on density-induced costs. …”
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Efficient secretion of a modified E7 protein from human papilloma virus type-16 by Lactococcus lactis por Quistián Martínez, Deyanira, Villatoro Hernández, Julio, Loera Arias, María de Jesús, Rangel Colmenero, Blanca Rocío, Zavala Flores, Laura Mireya, Sepúlveda Saavedra, Julio, Guzmán López, Santos, Elizondo Omaña, Rodrigo Enrique, Montes de Oca Luna, Roberto, Saucedo Cárdenas, Odila

“…Methods and Results: We cloned the coding sequence of a modified E7 (E7m)from the HPV-16 in a plasmid regulated by the strong expression promoter p59. Secretion of the E7m was made by the signal peptide of the usp45 gene.The E7m was detected by Western blot in the cell-free-medium fraction, showing no degradation or aberrant forms. …”
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Interacción del complejo WT1-Par4 con el promotor P1 DE Bcl-2 en la línea celular MCF7 en presencia y ausencia de estímulo estrogénico por Hernández Herrera, Anadulce

“…The inhibition of Par4 resulted in a reduction of WT1 expression however the Bcl-2 expression was not affected. …”
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Interacción del complejo WT1-Par4 con el promotor P1 DE Bcl-2 en la línea celular MCF7 en presencia y ausencia de estímulo estrogénico por Hernández Herrera, Anadulce

“…The inhibition of Par4 resulted in a reduction of WT1 expression however the Bcl-2 expression was not affected. …”
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Evaluación de la administración vía aerosol de la vacuna sintética basada en WT1-CPG en un modelo de cáncer pulmonar. por Arriaga Hernández, Daniela

“…Its restricted expression in normal tissue makes it an attractive target for cancer immunotherapy. …”
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Evaluación de la administración vía aerosol de la vacuna sintética basada en WT1-CPG en un modelo de cáncer pulmonar. por Arriaga Hernández, Daniela

“…Its restricted expression in normal tissue makes it an attractive target for cancer immunotherapy. …”
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Expresión de la proteína PAR-4 en pacientes con cáncer pulmonar y su asociación con el pronóstico de la enfermedad. por Carrizales Luna, Jorge Emmanuel

“…The molecular biology of this neoplasm shows resistance to apoptosis as a result of loss of the TP53 gene in more than 50% of patients and an overexpression of antiapoptotic proteins. …”
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Expresión de la proteína PAR-4 en pacientes con cáncer pulmonar y su asociación con el pronóstico de la enfermedad. por Carrizales Luna, Jorge Emmanuel

“…The molecular biology of this neoplasm shows resistance to apoptosis as a result of loss of the TP53 gene in more than 50% of patients and an overexpression of antiapoptotic proteins. …”
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Efecto patológico de la expansión de poliglutaminas de hTBP en la enfermedad neurodegenerativa SCA17 en Drosophila melanogaster por Cárdenas Tueme, Marcela

“…SCA17 is caused by an expansion of the CAG / CAA trinucleotide in the gene encoding polyQ regions in the human TBP protein (hTBP). …”
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Efecto patológico de la expansión de poliglutaminas de hTBP en la enfermedad neurodegenerativa SCA17 en Drosophila melanogaster por Cárdenas Tueme, Marcela

“…SCA17 is caused by an expansion of the CAG / CAA trinucleotide in the gene encoding polyQ regions in the human TBP protein (hTBP). …”
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Recent Understanding and Future Directions of Recurrent Corticotroph Tumors por Hinojosa Amaya, José Miguel, Lam Chung, César Ernesto, Cuevas Ramos, Daniel

“…Furthermore, functioning CTs develop resistance to glucocorticoid-mediated negative feedback on ACTH secretion, through increased expression of testicular orphan nuclear receptor 4 (TR4), heat-shock protein 90 (HSP90), and loss-of-function mutation of CDK5 and ABL enzyme substrate 1 (CABLES1) gene. …”
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Farmacogenética de la quimioterapia de los tumores gastrointestinales. por Castro Rojas, Carlos Andrés

“…None of the genotypes evaluated was associated with the expression (mRNA) of TS in tumor samples. Taking together these results, it is proposed that germ-line variants in the UTR regions of the TYMS gene are genetic biomakers for response and toxicity in fluoropyrimidine-based chemotherapy treatment of patients with avanzed gastrointestinal tumors. …”
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Farmacogenética de la quimioterapia de los tumores gastrointestinales. por Castro Rojas, Carlos Andrés

“…None of the genotypes evaluated was associated with the expression (mRNA) of TS in tumor samples. Taking together these results, it is proposed that germ-line variants in the UTR regions of the TYMS gene are genetic biomakers for response and toxicity in fluoropyrimidine-based chemotherapy treatment of patients with avanzed gastrointestinal tumors. …”
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Recent advances in the application of stable isotopes as nutritional tools in aquaculture por Gamboa Delgado, Julián, Peña Rodríguez, Alberto, Martínez Rocha, Luis, Villarreal Cavazos, David Alonso, Nieto López, Martha Guadalupe, Tapia Salazar, Mireya, Ricque Marie, Denis, Cruz Suárez, Lucía Elizabeth, Le Vay, Lewis, Fernández Díaz, Catalina, Cañavate, José Pedro, Ponce, Marian, Zerolo, Ricardo, Manchado, Manuel

“…In a third, multidisciplinary experiment, Senegalese sole (Solea senegalensis) larvae were used as a model to evaluate the effect of different larval feeding regimes on (1) trypsinogen gene expression (ssetryp1), (2) trypsin and chymotrypsin activities and (3) changes in stable isotope composition to estimate the assimilation of dietary carbon from the larval diets.…”
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Efecto del silenciamiento del gen WT-1 con ARNi en combinación con drogas anticancerígenas en modelo In vitro y en un modelo murino con metástasis a pulmón. por Thompson Armendáriz, Fernanda Guadalupe

“…In this work we investigated the potential of wt1 as a therapeutic target by exposing the murine melanoma line B16F10 to a complex of RNAi against wt1 (RNAi-wt1) in combination with chemotherapeutic drugs (Gemcitabine and Cisplatin), where a synergistic effect was determine by a isobologram; besides, a clonogenic test was performed, obtaining a decrease in the number of cell foci; in the PCR techniques a decrease in the expression of wt1 and the apoptotic gene bcl2 was observed; and in the cytometric test, a reduction in cell viability by apoptosis of 22% was found. …”
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Efecto del silenciamiento del gen WT-1 con ARNi en combinación con drogas anticancerígenas en modelo In vitro y en un modelo murino con metástasis a pulmón. por Thompson Armendáriz, Fernanda Guadalupe

“…In this work we investigated the potential of wt1 as a therapeutic target by exposing the murine melanoma line B16F10 to a complex of RNAi against wt1 (RNAi-wt1) in combination with chemotherapeutic drugs (Gemcitabine and Cisplatin), where a synergistic effect was determine by a isobologram; besides, a clonogenic test was performed, obtaining a decrease in the number of cell foci; in the PCR techniques a decrease in the expression of wt1 and the apoptotic gene bcl2 was observed; and in the cytometric test, a reduction in cell viability by apoptosis of 22% was found. …”
Enlace del recurso