Resultados de búsqueda - Brugg~

  1. 361
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    A pharmacogenetic pilot study reveals MTHFR, DRD3, and MDR1 polymorphisms as biomarker candidates for slow atorvastatin metabolizers por León Cachón, Rafael B. R., Ascacio Martínez, Jorge Ángel Isidro, Gamino Peña, María E., Cerda Flores, Ricardo Martín, Meester, Irene, Gallardo Blanco, Hugo Leonid, Gómez Silva, Magdalena, Piñeyro Garza, Everardo, Barrera Saldaña, Hugo Alberto

    Publicado 2016
    “…Aims of this study were: 1) to reveal the frequency of 87 polymorphisms in 36 genes related to drug metabolism in healthy Mexican volunteers, 2) to evaluate the impact of these polymorphisms on ATV pharmacokinetics, 3) to classify the ATV metabolic phenotypes of healthy volunteers, and 4) to investigate a possible association between genotypes and metabolizer phenotypes. …”
    Enlace del recurso
    Artículo
  3. 363
  4. 364

    Low-Dose Amphotericin B and Murine Dialyzable Spleen Extracts Protect against SystemicCandidaInfection in Mice por Robledo Ávila, F., Pérez Tapia, M., Limón Flores, A., Pavon, L., Hernández Pando, R., Wong Baeza, I., González González, Gloria María, Tovar, C., Estrada Parra, S., Estrada García, I.

    Publicado 2013
    “…Low-dose AmB and mDSE synergized to clear the infectious agent and reduced tissue damage, confirming the efficacy of a low dose of AmB, which might decrease the risk of drug toxicity. Further studies are necessary to explore these findings and its implications in future therapeutic approaches.…”
    Enlace del recurso
    Artículo
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    Alternativas para Cadena de Suministro Verde: El Caso del Aceite Mineral en la Industria Química Cosmética de México. por Barrera Ruíz, Arturo

    Publicado 2012
    “…Entre sus ventajas para la industria destacan su bajo costo y la aprobación de la FDA (U.S. Food and Drug Administration) como sustancia segura para el consumo humano de aplicación tópica; además de la aprobación otorgada por las normas mexicanas de regulación y fomento sanitario. …”
    Enlace del recurso
    Artículo
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    Synthesis, Biological Evaluation and Docking Studies of Chalcone and Flavone Analogs as Antioxidants and Acetylcholinesterase Inhibitors por Díaz Rubio, Laura, Hernández Martínez, Rufina, Estolano Cobián, Arturo, Chávez Velasco, Daniel, Salazar Aranda, Ricardo, Waksman de Torres, Noemí, Rivero, Ignacio, García González, Víctor, Ramos, Marco, Córdova Guerrero, Iván

    Publicado 2019
    “…Therefore, search for new or improved antioxidant molecules with acetylcholinesterase activity is essential to offer alternative chemotherapeutic agents to support current drug therapies. A series of chalcone (2a–2k) and flavone (3a–3k) analogs were synthesized, characterized, and evaluated as acetylcholinesterase (AChE) inhibitors, and antioxidant agents using 1,1-diphenyl-2-picrylhydrazyl (DPPH•), 2-20-azino-bis-(3-ethylbenzothiazoline-6-sulfonate) (ABTS•), and β-carotene/linoleic acid bleaching assay. …”
    Enlace del recurso
    Artículo
  15. 375

    Matriz polimérica elaborada por electrohilado a base de polivinilpirrolidona/gelatina y su aplicación biomédica por López Calderón, Héctor Daniel

    Publicado 2020
    “…The scaffold presents chemical composition, wettability characteristics, and antibacterial activity that fulfill the proposal from this work, based on obtaining a material that could be used as a drug delivery vehicle and a wound dressing material.…”
    Enlace del recurso
    Tesis
  16. 376
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    Outcomes of transitional care programs on adolescent chronic inflammatory systemic diseases: systematic review and meta-analyses por García Rodríguez, Fernando, Raygoza Cortez, Karina, Moreno Hernández, Lesli Michel, García Pérez, Rodrigo, Garza López, Leticia Elizabeth, Arana Guajardo, Ana Cecilia, Jáquez Quintana, Joel Omar, Villarreal Treviño, Ana Victoria, De la O Cavazos, Manuel Enrique, Rubio Pérez, Nadina

    Publicado 2022
    “…We extracted information regarding health-related quality of life, disease activity, drop-out rates, clinical attendance rates, hospital admission rates, disease-related knowledge, surgeries performed, drug toxicity and satisfaction rates. Results Fifteen studies met our inclusion criteria. …”
    Enlace del recurso
    Artículo
  18. 378

    In silico identification of peptides with PPARγ antagonism in protein hydrolysate from rice (Oryza sativa) por Ruíz López, Felipe de Jesús, Espinosa Rodríguez, Bryan Alejandro, Silva Mares, David Arturo, González Martínez, Blanca Edelia, López Cabanillas Lomelí, Manuel, Méndez López, Luis Fernando, Vázquez Rodríguez, Jesús Alberto

    Publicado 2023
    “…For the top candidates, molecular simulations were conducted using Autodock Vina to evaluate their binding affinity against the antiadipogenic region of PPARγ and their pharmacokinetics and drug-likeness using SwissADME. Simulating gastrointestinal digestion showed a recovery of 43.07% and 35.92% bioaccessibility. …”
    Enlace del recurso
    Artículo
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    Dissecting the epigenetic changes induced by non-antipsychotic mood stabilizers on schizophrenia and affective disorders: a systematic review por Gardea Resendez, Manuel, Kucuker, Mehmet Utku, Blacker, Caren J., Ho, Ada M. C., Croarkin, Paul E., Frye, Mark A., Veldic, Marin

    Publicado 2020
    “…Conclusions: An advanced understanding of the specific epigenetic changes induced by classic mood stabilizers in patients with major psychiatric disorders will facilitate personalized interventions. Further related drug discovery should target the induction of selective chromatin remodeling and gene-specific expression effects.…”
    Enlace del recurso
    Artículo

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