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  1. 1521

    Generación de un vars dirigido por el promotor del gen hGH-N para cánceres hipofisiarios by Espino Saldaña, Ángeles Edith

    Published 2005
    “…Como alternativa, se estudió el efecto oncolítico del VARS dirigido per la versión corta de 500 pb del promotor de hGH-N, el cual es una versión mas corta del promotor que se planeaba utilizar en este trabajo. Este VARS mostró ser específico y potente para células de hipófisis. …”
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    Tesis
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    Paleoclimatic modeling and phylogeography of least killifish, Heterandria formosa: insights into Pleistocene expansion-contraction dynamics and evolutionary history of North Americ... by Bagley, Justin C, Sandel, Michael, Travis, Joseph, Lozano Vilano, María de Lourdes, Johnson, Jerald B

    Published 2013
    “…Several other features of the genetic data were consistent with predictions derived from an expansion-contraction model: limited intraspecific divergence (e.g. mean mtDNA p-distance = 0.66%); a pattern of mtDNA diversity (mean Hd = 0.934; mean π = 0.007) consistent with rapid, recent population expansion; a lack of mtDNA isolation-by-distance; and clinal variation in allozyme diversity with higher diversity at lower latitudes near the predicted refugium. Statistical tests of mismatch distributions and coalescent simulations of the gene tree lent greater support to a scenario of post-glacial expansion and diversification from a single refugium than to any other model examined (e.g. multiple-refugia scenarios). …”
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    Article
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