Resultados de búsqueda - ((lines OR nfs) OR lncs)

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    WT1 silencing by RNAi synergizes with chemotherapeutic agents and induces chemosensitization to doxorubicin and cisplatin in B16F10 murine melanoma cells por Zapata Benavides, Pablo, Manilla Muñoz, Edgar, Zamora Ávila, Diana Elisa, Saavedra Alonso, Santiago, Franco Molina, Moisés Armides, Trejo Ávila, Laura M., Dávalos Aranda, Guillermo, Rodríguez Padilla, Cristina

    Publicado 2012
    “…The objectives of this study were to investigate whether WT1 silencing is capable of synergizing with chemotherapeutic agents and whether this silencing is capable of sensitizing cancer cells to doxorubicin and cisplatin in the B16F10 murine melanoma cell line. In the present study, B16F10 cells were simultaneously treated with median lethal doses (LD50s) of WT1-1 or WT1-2 small hairpin RNAs (shRNAs) and chemotherapeutic agents. …”
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    Artículo
  8. 248

    WT1 shRNA delivery using transferrin-conjugated PEG liposomes in an in vivo model of melanoma por Saavedra Alonso, Santiago, Zapata Benavides, Pablo, Chávez Escamilla, Ana Karina, Manilla Muñoz, Edgar, Zamora Ávila, Diana Elisa, Franco Molina, Moisés Armides, Rodríguez Padilla, Cristina

    Publicado 2016
    “…Formulations of transferrin (Tf)‑conjugated polyethylene glycol (PEG) liposomes loaded with short hairpin RNA (shRNA) against WT1 (Lip + RNAi + Tf), PEG liposomes loaded with shRNA against WT1 (Lip + RNAi), Tf‑conjugated PEG liposomes loaded with pEGFP‑N3 (Lip + GFP + Tf) and saline solution as negative control (untreated) were administered systemically to C57BL/6 mice implanted subcutaneously with a melanoma cell line. Tumor volume, body weight, tumor weight, survival and relative expression of WT1 were evaluated. …”
    Enlace del recurso
    Artículo
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    Comparative Pharmacokinetic Study Among 3 Metformin Formulations in Healthy Mexican Volunteers: A Single-Dose, Randomized, Open-Label, 3-Period Crossover Study por Montoya Eguía, Sandra Lucía, Garza Ocañas, Lourdes, Badillo Castañeda, Christian Tadeo, Tamez de la O, Eduardo Javier, Zanatta Calderón, María Teresa, Gómez Meza, Marco Vinicio, Garza Ulloa, Humberto Jesús

    Publicado 2015
    “…Type 2 diabetes mellitus is the most common form of diabetes. Metformin is a first-line drug for its treatment. In Mexico, there are 34 generic formulations of metformin, so brand-generic substitutions and generic-generic substitutions are a common practice. …”
    Enlace del recurso
    Artículo
  15. 255

    Binding of hnRNP H and U2AF65 to Respective G-codes and a Poly-Uridine Tract Collaborate in the N50-5'ss Selection of the REST N Exon in H69 Cells por Buratti, Emanuele, Ortuño Pineda, Carlos, Galindo Rosales, José Manuel, Calderón Salinas, José Victor, Villegas Sepúlveda, Nicolás, Saucedo Cárdenas, Odila, De Nova Ocampo, Mónica, Valdés, Jesús

    Publicado 2012
    “…In this work we analyzed some of the regulatory factors and elements involved in the preferred selection of the N50-5’ss (N50 activation) in the small cell lung cancer cell line H69. Wild type and mutant N exon/b-globin minigenes recapitulated N50 exon splicing in H69 cells, and showed that the N-PU and the G2-G3 elements are required for N50 exon splicing. …”
    Enlace del recurso
    Artículo
  16. 256
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    Paisaje natural y envejecimiento saludable en el lugar: el caso del Parque Nacional Cumbres de Monterrey (México) por Sánchez González, Diego, Adame Rivera, Lydia Marcela, Rodríguez Rodríguez, Vicente

    Publicado 2018
    “…In addition, it aims to boost this line research and generate sustainable quality of life policies to encourage the development and protection of natural landscapes in the region. …”
    Enlace del recurso
    Artículo
  18. 258

    Paisaje natural y envejecimiento saludable en el lugar: el caso del Parque Nacional Cumbres de Monterrey (México) por Sánchez González, Diego, Adame Rivera, Lydia Marcela, Rodríguez Rodríguez, Vicente

    Publicado 2018
    “…In addition, it aims to boost this line research and generate sustainable quality of life policies to encourage the development and protection of natural landscapes in the region. …”
    Enlace del recurso
    Artículo
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