Resultados de búsqueda - ((ligur OR ligar) OR (sigue OR ((migne OR line) OR (mile OR miles)))) 1

Stereochemical preference toward oncotarget: Design, synthesis and <i>in vitro</i> anticancer evaluation of diastereomeric &#x3B2;-lactams por Olazarán Santibáñez, Fabián Eliseo, Bandyopadhyay, Debasish, Carranza Rosales, Pilar, Rivera, Gildardo, Balderas Rentería, Isaías

“…A cis-β-lactam [(±)-Cis3-amino-1-phenyl-4-(p-tolyl) azetidin-2-one, 6C] was found to be more active (in vitro) than the marketed natural drug colchicine against SiHa and B16F10 (six times higher potency) cell lines. …”
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Suppression of cell migration is promoted by miR-944 through targeting of SIAH1 and PTP4A1 in breast cancer cells por Flores Pérez, Ali, Marchat, Laurence A., Rodríguez Cuevas, Sergio, Piña Bautista, Verónica, Fuentes Mera, Lizeth, Romero Zamora, Diana, Maciel Domínguez, Anabel, De la Cruz, Olga Hernández, Fonseca Sánchez, Miguel, Ruíz García, Erika, Astudillo de la Vega, Horacio, López Camarillo, César

“…The luciferase reporter assay was used to evaluate targeting of SIAH1, PTP4A1 and PRKCA genes by miR-944. SIAH1 protein levels were measured by Western blot. …”
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Resiliencia en el uso de las aplicaciones didácticas interactivas en Estudiantes Universitarios después de la pandemia. Estudio Comparativo por Pérez-Martínez, Katia Site, Saldaña-Pérez, Juan Enrique, Mendoza-Vargas, Marta Magdalena

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Interacción del complejo WT1-Par4 con el promotor P1 DE Bcl-2 en la línea celular MCF7 en presencia y ausencia de estímulo estrogénico por Hernández Herrera, Anadulce

“…In this work we propose to determinate the existence of a WT1-Par4 complex, its ability to bind the Bcl-2 promoter, and a possible relation with RE in the MCF7 cell line model, to aim it we used the cell culture, immunoprecipitation, Pull down and Western blot techniques. …”
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Interacción del complejo WT1-Par4 con el promotor P1 DE Bcl-2 en la línea celular MCF7 en presencia y ausencia de estímulo estrogénico por Hernández Herrera, Anadulce

“…In this work we propose to determinate the existence of a WT1-Par4 complex, its ability to bind the Bcl-2 promoter, and a possible relation with RE in the MCF7 cell line model, to aim it we used the cell culture, immunoprecipitation, Pull down and Western blot techniques. …”
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Factores que influyen en el proceso de aprendizaje en modalidad virtual durante la pandemia COVID-19 por Tovar Morales, María Teresa, Hernández Moreno, Laura Alicia, Hernández Saldaña, Ma. de Lourdes

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Fármacos epigenéticos con efecto en la actividad promotora del gen rb1 en células hepáticas humanas por Vargas Gómez, Jorge Eduardo

“…Previously it was observed that the expression of RB1 was increased in the presence of the epigenetic drugs isotretinoin and thalidomide in the HepG2 cell line. …”
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Fármacos epigenéticos con efecto en la actividad promotora del gen rb1 en células hepáticas humanas por Vargas Gómez, Jorge Eduardo

“…Previously it was observed that the expression of RB1 was increased in the presence of the epigenetic drugs isotretinoin and thalidomide in the HepG2 cell line. …”
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WT1 shRNA delivery using transferrin-conjugated PEG liposomes in an in vivo model of melanoma por Saavedra Alonso, Santiago, Zapata Benavides, Pablo, Chávez Escamilla, Ana Karina, Manilla Muñoz, Edgar, Zamora Ávila, Diana Elisa, Franco Molina, Moisés Armides, Rodríguez Padilla, Cristina

“…Formulations of transferrin (Tf)‑conjugated polyethylene glycol (PEG) liposomes loaded with short hairpin RNA (shRNA) against WT1 (Lip + RNAi + Tf), PEG liposomes loaded with shRNA against WT1 (Lip + RNAi), Tf‑conjugated PEG liposomes loaded with pEGFP‑N3 (Lip + GFP + Tf) and saline solution as negative control (untreated) were administered systemically to C57BL/6 mice implanted subcutaneously with a melanoma cell line. …”
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Metabolomic and biodirected phytochemical study of Hechtia glomerata, evaluation of its antibacterial and cytotoxic activity, and determination of the mechanism of action of one ac... por Stefani, Tommaso

“…For these reasons it was decided to focus on the CHCl3/MeOH extract, which presented activity against PC3 and was slightly active against MCF7 cell lines. A bioassay-guided directed study was also conducted on this extract showing fractions 3 and 4 as the most active ones. …”
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Metabolomic and biodirected phytochemical study of Hechtia glomerata, evaluation of its antibacterial and cytotoxic activity, and determination of the mechanism of action of one ac... por Stefani, Tommaso

“…For these reasons it was decided to focus on the CHCl3/MeOH extract, which presented activity against PC3 and was slightly active against MCF7 cell lines. A bioassay-guided directed study was also conducted on this extract showing fractions 3 and 4 as the most active ones. …”
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WT1 silencing by RNAi synergizes with chemotherapeutic agents and induces chemosensitization to doxorubicin and cisplatin in B16F10 murine melanoma cells por Zapata Benavides, Pablo, Manilla Muñoz, Edgar, Zamora Ávila, Diana Elisa, Saavedra Alonso, Santiago, Franco Molina, Moisés Armides, Trejo Ávila, Laura M., Dávalos Aranda, Guillermo, Rodríguez Padilla, Cristina

“…The objectives of this study were to investigate whether WT1 silencing is capable of synergizing with chemotherapeutic agents and whether this silencing is capable of sensitizing cancer cells to doxorubicin and cisplatin in the B16F10 murine melanoma cell line. …”
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Caracterización del daño morfológico en el área ca1 del hipocampo y deterioro funcional secundario a isquemia cerebral global en ratas envejecidas por Villarreal Silva, Eliud Enrique

“…Desafortunadamente, la mayoría de los modelos animales que reproducen un cuadro patológico no incluyen importantes variables que permitan extrapolar los resultados obtenidos a la investigación clínica (1). Un ejemplo de esta discrepancia clínicoexperimental es la relacionada con la isquemia cerebral y el envejecimiento. …”
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Caracterización del daño morfológico en el área ca1 del hipocampo y deterioro funcional secundario a isquemia cerebral global en ratas envejecidas por Villarreal Silva, Eliud Enrique

“…Desafortunadamente, la mayoría de los modelos animales que reproducen un cuadro patológico no incluyen importantes variables que permitan extrapolar los resultados obtenidos a la investigación clínica (1). Un ejemplo de esta discrepancia clínicoexperimental es la relacionada con la isquemia cerebral y el envejecimiento. …”
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Evaluación in vitro, ex – vivo e in silico de nuevos derivados de 1,4-naftoquinonas sobre epimastigote y tripomastigote de Trypanosoma cruzi por Becerra Ramos, Nohemi Alejandra

“…The compound Ce-Q9 (0.04 μM +0.02) was the one that stood out in strain INC-5 and compound Ce-Q11 (1.14 μM + 0.03) in NINOA strain, unlike the reference drug: nfx. …”
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Evaluación in vitro, ex – vivo e in silico de nuevos derivados de 1,4-naftoquinonas sobre epimastigote y tripomastigote de Trypanosoma cruzi por Becerra Ramos, Nohemi Alejandra

“…The compound Ce-Q9 (0.04 μM +0.02) was the one that stood out in strain INC-5 and compound Ce-Q11 (1.14 μM + 0.03) in NINOA strain, unlike the reference drug: nfx. …”
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Disintegrins extracted from totonacan rattlesnake (Crotalus totonacus) venom and their anti-adhesive and anti-migration effects on MDA-MB-231 and HMEC-1 cells por Rivas Mercado, Eric Abdel, Neri Castro, E., Bénard Valle, M., Rucavado Romero, A., Olvera Rodríguez, A., Zamudio Zuñiga, F., Alagón Cano, A., Garza Ocañas, Lourdes

“…Totonacin showed more potent cell adhesion inhibitory activity toward vitronectin in both cell lines. These results suggest a major affinity of totonacin toward αVβ3, α8β1, αVβ5, αVβ1, and αIIbβ3 integrins. …”
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Propuesta de implementación del aula ipad para la mejora en el aprendizaje en la materia de química de primer semestre del Colegio de Ciencias y Humanidades de la UJED por Martínez Vázquez, Karen Ivon, Hernández Pacheco, Luis Alonso

“…En este proyecto se analiza el uso de la tableta digital iPad en el aula en el marco del proyecto piloto del CCH-UJED por implementar una propuesta didáctica en la materia de química. …”
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Metabolomic profile and Bioassay-guided Phytochemical analysis of the Stems from Cissus trifoliata, evaluation of their Antibacterial and Cytotoxic activity, and determination of t... por Méndez López, Luis Fernando

“…The antibacterial activity was determined by the broth microdilution method and the cytotoxicity against cancer cell lines using the MTS proliferation assay. A bioassay-guided study of the CHCl3-MeOH extract was performed using WST-1 to identify the active constituents responsible for the antiproliferative effects against cancer cells. …”
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Metabolomic profile and Bioassay-guided Phytochemical analysis of the Stems from Cissus trifoliata, evaluation of their Antibacterial and Cytotoxic activity, and determination of t... por Méndez López, Luis Fernando

“…The antibacterial activity was determined by the broth microdilution method and the cytotoxicity against cancer cell lines using the MTS proliferation assay. A bioassay-guided study of the CHCl3-MeOH extract was performed using WST-1 to identify the active constituents responsible for the antiproliferative effects against cancer cells. …”
Enlace del recurso