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Polimorfismo de los genes que codifican para las proteínas VP4, VP7 y NSP4 de rotavirus y su asociación con la severidad de la diarrea by González Ochoa, Guadalupe

“…Abstract Of the viruses that cause gastroenteritis, rotavirus is the main causal agent of severe diarrhea; it causes the fence death 440,000 children per year at world-wide level. Some researchers point to proteins VP4, VP7 and NSP4 like pathogenicity factors; VP4 and VP7 are related with the penetration viral into epithelial cells and the synthesis of neutralization antibodies; NSP4 is the first described viral enterotoxin, which, by means of an increase in Ca2+ it triggers the diarrheic processes. …”
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Análisis de expresión de genes de Mycobacterium tuberculosis durante la infección a macrófagos by Barrios García, Hugo Brígido

“…THP-1 cells monolayers differentiated to macrophages by phorbol myristate acetate (PMA) were infected with M. tuberculosis strains CDC1551, H37Rv and DR689 with a variable multiplicity of infection (MOI): 10:1, 1:1 and 0.1:1 (bacteria:macrophage) and incubated at various time points. Cytotoxicity was observed as areas of clearing and cell agglomeration and the effect was dependent on bacilli inoculum and incubation time. …”
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Análisis de expresión de genes de Mycobacterium tuberculosis durante la infección a macrófagos by Barrios García, Hugo Brígido

“…THP-1 cells monolayers differentiated to macrophages by phorbol myristate acetate (PMA) were infected with M. tuberculosis strains CDC1551, H37Rv and DR689 with a variable multiplicity of infection (MOI): 10:1, 1:1 and 0.1:1 (bacteria:macrophage) and incubated at various time points. Cytotoxicity was observed as areas of clearing and cell agglomeration and the effect was dependent on bacilli inoculum and incubation time. …”
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