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Effectiveness of subcutaneous low-dose alemtuzumab and rituximab combination therapy for steroid-resistant chronic graft-versus-host disease by Gutiérrez Aguirre, César Homero, Cantú Rodríguez, Olga Graciela, Borjas Almaguer, Omar David, González Llano, Óscar, Jaime Pérez, José Carlos, Solano Genesta, M., Gómez Guijosa, Miguel Ángel, Mancías Guerra, Consuelo, Tarín Arzaga, Luz del Carmen, Gómez Almaguer, David

“…Corticosteroids are the standard initial treatment. Second-line treatment has not been well defined. We evaluated the effectiveness and safety of low doses of alemtuzumab plus low doses of rituximab in the treatment of steroid-refractory chronic graftversus-host disease. …”
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Chitosan gold nanoparticles induce cell death in HeLa and MCF-7 cells through reactive oxygen species production by Martínez Torres, Ana Carolina, Zárate Triviño, Diana Ginette, Lorenzo Anota, Helen Yarimet, Avila Ávila, Andrea, Rodríguez Abrego, Carolina, Rodríguez Padilla, Cristina

“…In both HeLa and MCF-7 cell lines, CH-AuNPs inhibit clonogenic potential without inducing cell cycle arrest or nuclear alterations. …”
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Risk factors and molecular mechanisms associated with trimethoprim–sulfamethoxazole resistance in Stenotrophomonas maltophilia in Mexico by Herrera Heredia, Sandra Abril, Pezina Cantú, César Octaviano, Garza González, Elvira, Bocanegra Ibarias, Paola, Mendoza Olazarán, Soraya Sarahí, Morfín Otero, Rayo, Camacho Ortiz, Adrián, Villarreal Treviño, Licet, Rodríguez Noriega, Eduardo, Palau Davila, Laura, Maldonado Garza, Héctor Jesús, Flores Treviño, Samantha Maribel

“…Given the high SXT resistance rate, SXT is not an effective first-line therapy for our patients; instead, levofloxacin could be used as an appropriate therapeutic option against S. maltophilia infections.…”
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Cell death effect of CD47-agonist peptides on different types of leukemia and in a murine model by Uscanga Palomeque, Ashanti Concepción

“…To achieve this, cell death was evaluated, analyzing phosphatidylserine exposure (Ann-V), cell membrane permeabilization (PI), response to caspase inhibitor (Q-VD-OPh) and calcium chelator (BAPTA) in the different leukemic cell lines, in a murine T cell tumor lymphoblast cell line (L5178Y-R) and in PBMC and murine lymphoid cells. …”
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WT1 silencing by RNAi synergizes with chemotherapeutic agents and induces chemosensitization to doxorubicin and cisplatin in B16F10 murine melanoma cells by Zapata Benavides, Pablo, Manilla Muñoz, Edgar, Zamora Ávila, Diana Elisa, Saavedra Alonso, Santiago, Franco Molina, Moisés Armides, Trejo Ávila, Laura M., Dávalos Aranda, Guillermo, Rodríguez Padilla, Cristina

“…The objectives of this study were to investigate whether WT1 silencing is capable of synergizing with chemotherapeutic agents and whether this silencing is capable of sensitizing cancer cells to doxorubicin and cisplatin in the B16F10 murine melanoma cell line. In the present study, B16F10 cells were simultaneously treated with median lethal doses (LD50s) of WT1-1 or WT1-2 small hairpin RNAs (shRNAs) and chemotherapeutic agents. …”
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WT1 shRNA delivery using transferrin-conjugated PEG liposomes in an in vivo model of melanoma by Saavedra Alonso, Santiago, Zapata Benavides, Pablo, Chávez Escamilla, Ana Karina, Manilla Muñoz, Edgar, Zamora Ávila, Diana Elisa, Franco Molina, Moisés Armides, Rodríguez Padilla, Cristina

“…Formulations of transferrin (Tf)‑conjugated polyethylene glycol (PEG) liposomes loaded with short hairpin RNA (shRNA) against WT1 (Lip + RNAi + Tf), PEG liposomes loaded with shRNA against WT1 (Lip + RNAi), Tf‑conjugated PEG liposomes loaded with pEGFP‑N3 (Lip + GFP + Tf) and saline solution as negative control (untreated) were administered systemically to C57BL/6 mice implanted subcutaneously with a melanoma cell line. Tumor volume, body weight, tumor weight, survival and relative expression of WT1 were evaluated. …”
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Cell death effect of CD47-agonist peptides on different types of leukemia and in a murine model by Uscanga Palomeque, Ashanti Concepción

“…To achieve this, cell death was evaluated, analyzing phosphatidylserine exposure (Ann-V), cell membrane permeabilization (PI), response to caspase inhibitor (Q-VD-OPh) and calcium chelator (BAPTA) in the different leukemic cell lines, in a murine T cell tumor lymphoblast cell line (L5178Y-R) and in PBMC and murine lymphoid cells. …”
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Propuestas temáticas de oposición en plataformas electorales y spots político-electorales: El caso del PAN, PRD y MORENA en las elecciones a gobernador en el Estado de México 2017... by Alva Rivera, Miguel Eduardo, Díaz Jiménez, Oniel Francisco

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Capacidad tecnológica, una estrategia de aprovechamiento glocal en el uso de Internet como Fuente de Información en Venezuela by Gutiérrez, Siglic, Mogollón, Hazel

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Estrategias para el desarrollo cinematográfico comercial mexicano hacia los Estados Unidos by Lozano, David, Barragán, José N., Guerra, Sergio, Zúñiga, Jorge

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Gestión de conflictos y Cultura de Paz: investigación y aplicaciones en contextos formales e informales by Morales Quintero , Luz Anyela, González Martín, Nuria

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Las empresas familiares como base en el desarrollo económico local en el estado de San Luis Potosí by González-Garfias, Rocío, Aguilera-Alejo, Guillermo

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Desarrollo de competencias a través de un proyecto multidisciplinario by Alanís Hernández, Blanca, Ling, Ma. de los Angeles de, Santos Lara, Mirna Elizabeth, Briones Ortiz, Nancy Patricia, Osorio de Dios, Sylvia, Gaitán Vigil, Clemente Carmen

“…El fundamento para el presente proyecto ha sido la Visión UANL 2012 en la cual se establece que “las Tecnologías de Información y Comunicación contribuyen a la creación de ambientes para el aprendizaje, entendidos, estos como situaciones educativas centradas en el estudiante, que favorecen el aprendizaje autodirigido y el desarrollo del pensamiento reflexivo y crítico”, así mismo, que el modelo educativo deberá contemplar el rediseño curricular centrado en el aprendizaje, un enfoque transversal de la currícula que incoprpore persepctivas multi, inter y transdisciplinarias y la incorporación del uso de la tecnologías de Información y Comunicación (TIC) en los procesos de enseñanza aprendizaje. De esta manera organizamos el trabajo en 21 equipos multidisciplinarios constituidos por 1 mercadólogo, 1-2 publicistas, 3-4 nutriólogos. …”
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Software educativo y de autoevaluación para materias de ciencias básicas de las carreras de ingeniería. by Rosas Toro, María Alejandra, Rosas Aguilar, Carmen Julia, Bridat Cruz, Alicia Magdalena, Cantor Gandarilla, Benito

“…El diseño fue centrado en el estudiante utilizando las teorías de aprendizaje modernas, y las Tecnologías de la Información y Comunicación (TIC) aplicadas a la educación, por lo que puede ser usado como parte de las actividades del aprendizaje constructivista y significativo que requieren los estudiantes de acuerdo al Modelo Educativo del Tecnológico Nacional de México. …”
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La Tecnología como intercambio de información, Actividad Física y Nutrición en Estudiantes Universitarios by Rodríguez Vela, Brenda Rocío, Tapia Martinez, José René, Gallegos-Sánchez, Jesús José

“…Las tecnologías de la información y la comunicación (TIC´S) se han convertido en un elemento indispensable que de una u otra forma condiciona nuestras vidas.…”
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Comparative Pharmacokinetic Study Among 3 Metformin Formulations in Healthy Mexican Volunteers: A Single-Dose, Randomized, Open-Label, 3-Period Crossover Study by Montoya Eguía, Sandra Lucía, Garza Ocañas, Lourdes, Badillo Castañeda, Christian Tadeo, Tamez de la O, Eduardo Javier, Zanatta Calderón, María Teresa, Gómez Meza, Marco Vinicio, Garza Ulloa, Humberto Jesús

“…Type 2 diabetes mellitus is the most common form of diabetes. Metformin is a first-line drug for its treatment. In Mexico, there are 34 generic formulations of metformin, so brand-generic substitutions and generic-generic substitutions are a common practice. …”
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Binding of hnRNP H and U2AF65 to Respective G-codes and a Poly-Uridine Tract Collaborate in the N50-5'ss Selection of the REST N Exon in H69 Cells by Buratti, Emanuele, Ortuño Pineda, Carlos, Galindo Rosales, José Manuel, Calderón Salinas, José Victor, Villegas Sepúlveda, Nicolás, Saucedo Cárdenas, Odila, De Nova Ocampo, Mónica, Valdés, Jesús

“…In this work we analyzed some of the regulatory factors and elements involved in the preferred selection of the N50-5’ss (N50 activation) in the small cell lung cancer cell line H69. Wild type and mutant N exon/b-globin minigenes recapitulated N50 exon splicing in H69 cells, and showed that the N-PU and the G2-G3 elements are required for N50 exon splicing. …”
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Maternal overnutrition by hypercaloric diets programs hypothalamic mitochondrial fusion and metabolic dysfunction in rat male offspring by Cárdenas Pérez, Robbi Elizabeth, Fuentes Mera, Lizeth, De la Garza, Ana Laura, Torre Villalvazo, Iván, Reyes Castro, Luis A., Rodríguez Rocha, Humberto, García García, Aracely, Corona Castillo, Juan Carlos, Tovar, Armando R., Zambrano, Elena, Ortiz López, Rocío, Saville, Jennifer, Fuller, Maria, Camacho Morales, Alberto

“…Mitochondrial-ER function was analyzed by confocal microscopy using hypothalamic cell line mHypoA-CLU192. Results: Maternal programming by HFD and CAF leads to failure in glucose, leptin and insulin sensitivity and fat accumulation. …”
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Paisaje natural y envejecimiento saludable en el lugar: el caso del Parque Nacional Cumbres de Monterrey (México) by Sánchez González, Diego, Adame Rivera, Lydia Marcela, Rodríguez Rodríguez, Vicente

“…In addition, it aims to boost this line research and generate sustainable quality of life policies to encourage the development and protection of natural landscapes in the region. …”
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Paisaje natural y envejecimiento saludable en el lugar: el caso del Parque Nacional Cumbres de Monterrey (México) by Sánchez González, Diego, Adame Rivera, Lydia Marcela, Rodríguez Rodríguez, Vicente

“…In addition, it aims to boost this line research and generate sustainable quality of life policies to encourage the development and protection of natural landscapes in the region. …”
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