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81
Redes femeninas, familia popular y ancianidad en Venezuela.
Publicado 2008Enlace del recurso
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82
Metabolomic and biodirected phytochemical study of Hechtia glomerata, evaluation of its antibacterial and cytotoxic activity, and determination of the mechanism of action of one ac...
Publicado 2020“…For these reasons it was decided to focus on the CHCl3/MeOH extract, which presented activity against PC3 and was slightly active against MCF7 cell lines. A bioassay-guided directed study was also conducted on this extract showing fractions 3 and 4 as the most active ones. …”
Enlace del recurso
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83
Metabolomic and biodirected phytochemical study of Hechtia glomerata, evaluation of its antibacterial and cytotoxic activity, and determination of the mechanism of action of one ac...
Publicado 2020“…For these reasons it was decided to focus on the CHCl3/MeOH extract, which presented activity against PC3 and was slightly active against MCF7 cell lines. A bioassay-guided directed study was also conducted on this extract showing fractions 3 and 4 as the most active ones. …”
Enlace del recurso
Tesis -
84
WT1 silencing by RNAi synergizes with chemotherapeutic agents and induces chemosensitization to doxorubicin and cisplatin in B16F10 murine melanoma cells
Publicado 2012“…The objectives of this study were to investigate whether WT1 silencing is capable of synergizing with chemotherapeutic agents and whether this silencing is capable of sensitizing cancer cells to doxorubicin and cisplatin in the B16F10 murine melanoma cell line. …”
Enlace del recurso
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85
Evaluación in vitro, ex – vivo e in silico de nuevos derivados de 1,4-naftoquinonas sobre epimastigote y tripomastigote de Trypanosoma cruzi
Publicado 2018“…The compound Ce-Q9 (0.04 μM +0.02) was the one that stood out in strain INC-5 and compound Ce-Q11 (1.14 μM + 0.03) in NINOA strain, unlike the reference drug: nfx. …”
Enlace del recurso
Tesis -
86
Evaluación in vitro, ex – vivo e in silico de nuevos derivados de 1,4-naftoquinonas sobre epimastigote y tripomastigote de Trypanosoma cruzi
Publicado 2018“…The compound Ce-Q9 (0.04 μM +0.02) was the one that stood out in strain INC-5 and compound Ce-Q11 (1.14 μM + 0.03) in NINOA strain, unlike the reference drug: nfx. …”
Enlace del recurso
Tesis -
87
Disintegrins extracted from totonacan rattlesnake (Crotalus totonacus) venom and their anti-adhesive and anti-migration effects on MDA-MB-231 and HMEC-1 cells
Publicado 2020“…Totonacin showed more potent cell adhesion inhibitory activity toward vitronectin in both cell lines. These results suggest a major affinity of totonacin toward αVβ3, α8β1, αVβ5, αVβ1, and αIIbβ3 integrins. …”
Enlace del recurso
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88
Metabolomic profile and Bioassay-guided Phytochemical analysis of the Stems from Cissus trifoliata, evaluation of their Antibacterial and Cytotoxic activity, and determination of t...
Publicado 2020“…The antibacterial activity was determined by the broth microdilution method and the cytotoxicity against cancer cell lines using the MTS proliferation assay. A bioassay-guided study of the CHCl3-MeOH extract was performed using WST-1 to identify the active constituents responsible for the antiproliferative effects against cancer cells. …”
Enlace del recurso
Tesis -
89
Metabolomic profile and Bioassay-guided Phytochemical analysis of the Stems from Cissus trifoliata, evaluation of their Antibacterial and Cytotoxic activity, and determination of t...
Publicado 2020“…The antibacterial activity was determined by the broth microdilution method and the cytotoxicity against cancer cell lines using the MTS proliferation assay. A bioassay-guided study of the CHCl3-MeOH extract was performed using WST-1 to identify the active constituents responsible for the antiproliferative effects against cancer cells. …”
Enlace del recurso
Tesis -
90
Efecto del silenciamiento del gen WT-1 con ARNi en combinación con drogas anticancerígenas en modelo In vitro y en un modelo murino con metástasis a pulmón.
Publicado 2018“…In addition, it is an oncogene overexpressed in various carcinomas, including the lung, and antisense oligos have been used for wt1 that suppress the growth of lung cell lines (Oji et al., 1999). …”
Enlace del recurso
Tesis -
91
Efecto del silenciamiento del gen WT-1 con ARNi en combinación con drogas anticancerígenas en modelo In vitro y en un modelo murino con metástasis a pulmón.
Publicado 2018“…In addition, it is an oncogene overexpressed in various carcinomas, including the lung, and antisense oligos have been used for wt1 that suppress the growth of lung cell lines (Oji et al., 1999). …”
Enlace del recurso
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Reseña y análisis de la película “Tiempos modernos” de Charles Chaplin
Publicado 2022Enlace del recurso
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Implementación de las 5s enfocado en líneas de producción
Publicado 2024Enlace del recurso
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Hyperpigmentation of hard palate induced by chloroquine therapy
Publicado 2017Enlace del recurso
Artículo