Resultados de búsqueda - (((anza OR line) OR (tics OR tic)) OR (((enina OR enine) OR lenica) OR (gtgrenina OR tenica)))*

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    Cell death effect of CD47-agonist peptides on different types of leukemia and in a murine model por Uscanga Palomeque, Ashanti Concepción

    Publicado 2018
    “…To achieve this, cell death was evaluated, analyzing phosphatidylserine exposure (Ann-V), cell membrane permeabilization (PI), response to caspase inhibitor (Q-VD-OPh) and calcium chelator (BAPTA) in the different leukemic cell lines, in a murine T cell tumor lymphoblast cell line (L5178Y-R) and in PBMC and murine lymphoid cells. …”
    Enlace del recurso
    Tesis
  13. 353

    WT1 silencing by RNAi synergizes with chemotherapeutic agents and induces chemosensitization to doxorubicin and cisplatin in B16F10 murine melanoma cells por Zapata Benavides, Pablo, Manilla Muñoz, Edgar, Zamora Ávila, Diana Elisa, Saavedra Alonso, Santiago, Franco Molina, Moisés Armides, Trejo Ávila, Laura M., Dávalos Aranda, Guillermo, Rodríguez Padilla, Cristina

    Publicado 2012
    “…The objectives of this study were to investigate whether WT1 silencing is capable of synergizing with chemotherapeutic agents and whether this silencing is capable of sensitizing cancer cells to doxorubicin and cisplatin in the B16F10 murine melanoma cell line. In the present study, B16F10 cells were simultaneously treated with median lethal doses (LD50s) of WT1-1 or WT1-2 small hairpin RNAs (shRNAs) and chemotherapeutic agents. …”
    Enlace del recurso
    Artículo
  14. 354

    WT1 shRNA delivery using transferrin-conjugated PEG liposomes in an in vivo model of melanoma por Saavedra Alonso, Santiago, Zapata Benavides, Pablo, Chávez Escamilla, Ana Karina, Manilla Muñoz, Edgar, Zamora Ávila, Diana Elisa, Franco Molina, Moisés Armides, Rodríguez Padilla, Cristina

    Publicado 2016
    “…Formulations of transferrin (Tf)‑conjugated polyethylene glycol (PEG) liposomes loaded with short hairpin RNA (shRNA) against WT1 (Lip + RNAi + Tf), PEG liposomes loaded with shRNA against WT1 (Lip + RNAi), Tf‑conjugated PEG liposomes loaded with pEGFP‑N3 (Lip + GFP + Tf) and saline solution as negative control (untreated) were administered systemically to C57BL/6 mice implanted subcutaneously with a melanoma cell line. Tumor volume, body weight, tumor weight, survival and relative expression of WT1 were evaluated. …”
    Enlace del recurso
    Artículo
  15. 355

    Cell death effect of CD47-agonist peptides on different types of leukemia and in a murine model por Uscanga Palomeque, Ashanti Concepción

    Publicado 2018
    “…To achieve this, cell death was evaluated, analyzing phosphatidylserine exposure (Ann-V), cell membrane permeabilization (PI), response to caspase inhibitor (Q-VD-OPh) and calcium chelator (BAPTA) in the different leukemic cell lines, in a murine T cell tumor lymphoblast cell line (L5178Y-R) and in PBMC and murine lymphoid cells. …”
    Enlace del recurso
    Tesis
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