Resultados de búsqueda - ((((sigue OR miguel) OR line) OR ((linan OR (giran OR gira)) OR lira)) OR (ligule OR ligur)) 1

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    Fármacos epigenéticos con efecto en la actividad promotora del gen rb1 en células hepáticas humanas por Vargas Gómez, Jorge Eduardo

    Publicado 2019
    “…Previously it was observed that the expression of RB1 was increased in the presence of the epigenetic drugs isotretinoin and thalidomide in the HepG2 cell line. …”
    Enlace del recurso
    Tesis
  7. 67

    Fármacos epigenéticos con efecto en la actividad promotora del gen rb1 en células hepáticas humanas por Vargas Gómez, Jorge Eduardo

    Publicado 2019
    “…Previously it was observed that the expression of RB1 was increased in the presence of the epigenetic drugs isotretinoin and thalidomide in the HepG2 cell line. …”
    Enlace del recurso
    Tesis
  8. 68

    WT1 shRNA delivery using transferrin-conjugated PEG liposomes in an in vivo model of melanoma por Saavedra Alonso, Santiago, Zapata Benavides, Pablo, Chávez Escamilla, Ana Karina, Manilla Muñoz, Edgar, Zamora Ávila, Diana Elisa, Franco Molina, Moisés Armides, Rodríguez Padilla, Cristina

    Publicado 2016
    “…Formulations of transferrin (Tf)‑conjugated polyethylene glycol (PEG) liposomes loaded with short hairpin RNA (shRNA) against WT1 (Lip + RNAi + Tf), PEG liposomes loaded with shRNA against WT1 (Lip + RNAi), Tf‑conjugated PEG liposomes loaded with pEGFP‑N3 (Lip + GFP + Tf) and saline solution as negative control (untreated) were administered systemically to C57BL/6 mice implanted subcutaneously with a melanoma cell line. …”
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    Artículo
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    Metabolomic and biodirected phytochemical study of Hechtia glomerata, evaluation of its antibacterial and cytotoxic activity, and determination of the mechanism of action of one ac... por Stefani, Tommaso

    Publicado 2020
    “…For these reasons it was decided to focus on the CHCl3/MeOH extract, which presented activity against PC3 and was slightly active against MCF7 cell lines. A bioassay-guided directed study was also conducted on this extract showing fractions 3 and 4 as the most active ones. …”
    Enlace del recurso
    Tesis
  14. 74

    Metabolomic and biodirected phytochemical study of Hechtia glomerata, evaluation of its antibacterial and cytotoxic activity, and determination of the mechanism of action of one ac... por Stefani, Tommaso

    Publicado 2020
    “…For these reasons it was decided to focus on the CHCl3/MeOH extract, which presented activity against PC3 and was slightly active against MCF7 cell lines. A bioassay-guided directed study was also conducted on this extract showing fractions 3 and 4 as the most active ones. …”
    Enlace del recurso
    Tesis
  15. 75

    WT1 silencing by RNAi synergizes with chemotherapeutic agents and induces chemosensitization to doxorubicin and cisplatin in B16F10 murine melanoma cells por Zapata Benavides, Pablo, Manilla Muñoz, Edgar, Zamora Ávila, Diana Elisa, Saavedra Alonso, Santiago, Franco Molina, Moisés Armides, Trejo Ávila, Laura M., Dávalos Aranda, Guillermo, Rodríguez Padilla, Cristina

    Publicado 2012
    “…The objectives of this study were to investigate whether WT1 silencing is capable of synergizing with chemotherapeutic agents and whether this silencing is capable of sensitizing cancer cells to doxorubicin and cisplatin in the B16F10 murine melanoma cell line. …”
    Enlace del recurso
    Artículo
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    Caracterización del daño morfológico en el área ca1 del hipocampo y deterioro funcional secundario a isquemia cerebral global en ratas envejecidas por Villarreal Silva, Eliud Enrique

    Publicado 2014
    “…Desafortunadamente, la mayoría de los modelos animales que reproducen un cuadro patológico no incluyen importantes variables que permitan extrapolar los resultados obtenidos a la investigación clínica (1). Un ejemplo de esta discrepancia clínicoexperimental es la relacionada con la isquemia cerebral y el envejecimiento. …”
    Enlace del recurso
    Tesis
  17. 77

    Caracterización del daño morfológico en el área ca1 del hipocampo y deterioro funcional secundario a isquemia cerebral global en ratas envejecidas por Villarreal Silva, Eliud Enrique

    Publicado 2014
    “…Desafortunadamente, la mayoría de los modelos animales que reproducen un cuadro patológico no incluyen importantes variables que permitan extrapolar los resultados obtenidos a la investigación clínica (1). Un ejemplo de esta discrepancia clínicoexperimental es la relacionada con la isquemia cerebral y el envejecimiento. …”
    Enlace del recurso
    Tesis
  18. 78

    Evaluación in vitro, ex – vivo e in silico de nuevos derivados de 1,4-naftoquinonas sobre epimastigote y tripomastigote de Trypanosoma cruzi por Becerra Ramos, Nohemi Alejandra

    Publicado 2018
    “…The compound Ce-Q9 (0.04 μM +0.02) was the one that stood out in strain INC-5 and compound Ce-Q11 (1.14 μM + 0.03) in NINOA strain, unlike the reference drug: nfx. …”
    Enlace del recurso
    Tesis
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    Evaluación in vitro, ex – vivo e in silico de nuevos derivados de 1,4-naftoquinonas sobre epimastigote y tripomastigote de Trypanosoma cruzi por Becerra Ramos, Nohemi Alejandra

    Publicado 2018
    “…The compound Ce-Q9 (0.04 μM +0.02) was the one that stood out in strain INC-5 and compound Ce-Q11 (1.14 μM + 0.03) in NINOA strain, unlike the reference drug: nfx. …”
    Enlace del recurso
    Tesis
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