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Stereochemical preference toward oncotarget: Design, synthesis and <i>in vitro</i> anticancer evaluation of diastereomeric β-lactams
Publicado 2017“…A cis-β-lactam [(±)-Cis3-amino-1-phenyl-4-(p-tolyl) azetidin-2-one, 6C] was found to be more active (in vitro) than the marketed natural drug colchicine against SiHa and B16F10 (six times higher potency) cell lines. …”
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79
Suppression of cell migration is promoted by miR-944 through targeting of SIAH1 and PTP4A1 in breast cancer cells
Publicado 2016“…The luciferase reporter assay was used to evaluate targeting of SIAH1, PTP4A1 and PRKCA genes by miR-944. SIAH1 protein levels were measured by Western blot. …”
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80