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Polimorfismo de los genes que codifican para las proteínas VP4, VP7 y NSP4 de rotavirus y su asociación con la severidad de la diarrea por González Ochoa, Guadalupe

“…Abstract Of the viruses that cause gastroenteritis, rotavirus is the main causal agent of severe diarrhea; it causes the fence death 440,000 children per year at world-wide level. Some researchers point to proteins VP4, VP7 and NSP4 like pathogenicity factors; VP4 and VP7 are related with the penetration viral into epithelial cells and the synthesis of neutralization antibodies; NSP4 is the first described viral enterotoxin, which, by means of an increase in Ca2+ it triggers the diarrheic processes. …”
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