Resultados de búsqueda - "novel"
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Temporal distribution and genetic variants in influenza A(H1N1)pdm09 virus circulating in Mexico, seasons 2012 and 2013
Publicado 2017“…We discuss the significance of these novel genetic changes.…”
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142
Statistically coherent calibration of X-Ray Fluorescence Spectrometry for major elements in rocks in minerals.
Publicado 2018“…Similar sensitivity (∼2.69–46.17 kc·s1·%1 for the OLR and ∼2.78–59.69 kc·s1·%1 for the UWLR) also indicated that the UWLR could advantageously replace the OLR model. Another novel aspect is that the total uncertainty can be reported for individual chemical data. …”
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143
Vasodilator Activity of Compounds Isolated from Plants Used in Mexican Traditional Medicine
Publicado 2018“…In this study, we carried out the screening of 19 compounds (triterpenes, diterpenes, sesquiterpenes, lignans, and flavonoids) isolated from 10 plants used in Mexican traditional medicine to determine whether they elicited vascular smooth muscle relaxation and, therefore, could represent novel anti-hypertension drug candidates. The vasorelaxant activity of these compounds was evaluated on the isolated rat aorta assay and the results obtained from this evaluation showed that three compounds induced a significant vasodilatory effect: meso-dihydroguaiaretic acid [half maximal effective concentration (EC50), 49.9 ± 11.2 µM; maximum effect (Emax), 99.8 ± 2.7%]; corosolic acid (EC50, 108.9 ± 6.7 µM; Emax, 96.4 ± 4.2%); and 5,8,40-trihydroxy-3,7-dimethoxyflavone (EC50, 122.3 ± 7.6 µM; Emax, 99.5 ± 5.4%). …”
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144
Integrating genomic analysis with the genetic basis of gene expression: Preliminary Evidence of the Identification of causal genes for cardiovascular and metabolic traits related...
Publicado 2012“…Whole-transcriptome expression profiling provides novel phenotypes for analysis of complex traits. …”
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145
Ectopic BAT mUCP-1 overexpression in SKM by delivering a BMP7/PRDM16/PGC-1a gene cocktail or single PRMD16 using non-viral UTMD gene therapy
Publicado 2018“…We used ultrasound-targeted microbubble destruction (UTMD), a novel targeted, non-viral approach to gene therapy, to deliver genes in the BAT differentiation pathway into rodent SKM to engineer a thermogenic BAT phenotype with ectopic mUCP-1 overexpression. …”
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146
Re-sensitizing Ampicillin and Kanamycin-Resistant E. coli and S. aureus Using Synergistic Metal Micronutrients-Antibiotic Combinations
Publicado 2020“…Due to the recent emergence of multi-drug resistant strains, the development of novel antimicrobial agents has become a critical issue. …”
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147
In silico identification of peptides with PPARγ antagonism in protein hydrolysate from rice (Oryza sativa)
Publicado 2023“…In this study, the digestibility and bioaccessibility in vitro of a novel protein concentrate (NPC) from rice were determined through INFOGEST protocols. …”
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148
Detección de microRNAs extracelulares y su potencial como biomarcadores moleculares
Publicado 2015“…The combination of 2 and 3 miRNAs used as a group in tissue and serum respectively, significantly increases the efficiency of the test and shows that miRNAs have potential as novel noninvasive biomarkers in breast cancer detection. …”
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Respuesta en frecuencia para sistemas en espacio de estados
Publicado 2023Enlace del recurso
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La represión a los movimientos anti-sistémicos en El Apando de José Revueltas
Publicado 2021Enlace del recurso
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Stereochemical preference toward oncotarget: Design, synthesis and <i>in vitro</i> anticancer evaluation of diastereomeric β-lactams
Publicado 2017“…ABSTRACT Purpose: In the battle against cancer discovery of new and novel chemotherapeutic agent demands extreme obligation. …”
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156
Recent Understanding and Future Directions of Recurrent Corticotroph Tumors
Publicado 2021“…This review summarizes the molecular mechanisms related to CTs tumorigenesis, their diagnostic approach, and provides an update of the potential novel therapies, from the lab bench to the clinical translation.…”
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157
WT1 shRNA delivery using transferrin-conjugated PEG liposomes in an in vivo model of melanoma
Publicado 2016“…Current treatments are largely ineffective; thus, novel gene delivery approaches that target tumor‑specific markers may be useful for the treatment of melanoma. …”
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Preventing bisphosphonate induced osteonecrosis of the jaw with a polyguanidine conjugate (GuaDex): a promising new approach
Publicado 2024“…This study introduces a novel ONJ model in rats by combining exposure to bisphosphonates, oral surgery, and bacterial inoculation. …”
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159
Producción de bioelectricidad utilizando nanofibras duales de TiO2/carbón como electrodo de una celda de combustible microbiana
Publicado 2015“…ABSTRACT In summary, we present a novel material composed of dual nanofibers of TiO2(rutile)-C(semi-graphitic)/C(semi-graphitic) with interesting morphological and electrical properties. …”
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Sueños de libertad: hadas, amor y resistencia en la España de la posguerra
Publicado 2024Enlace del recurso
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