Cell death effect of CD47-agonist peptides on different types of leukemia and in a murine model
Recently, it has been demonstrated that peptides derived from the C-terminal domain of the TSP1 (4N1K and PKHB1) can activate CD47 and cause caspase-independent and calcium dependent regulated cell death (RCD) selectively in cells of patients with chronic lymphocytic leukemia (CLL). Therefore, the a...
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| Format: | Tesis |
| Language: | English |
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2018
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| Online Access: | http://eprints.uanl.mx/21787/1/1080315045.pdf |