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Study of the mechanism of cell death caused by peptides targeting CD47 in leukemia cell lines.

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CD47 activation through the C-terminus of thrombospondin-1 or its derived peptides (4N1K and PKHB1) induce regulated cell death (RCD) in several types of cancer. Recently, it was demonstrated that PKHB1, the first serum-stable CD47 agonist peptide, induce caspase-independent, calcium-dependent RCD i...

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Bibliographic Details
Main Author:	Gómez Morales, Luis
Format:	Tesis
Language:	English
Published:	2017
Online Access:	http://eprints.uanl.mx/14460/1/1080252237.pdf

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