Study of the mechanism of cell death caused by peptides targeting CD47 in leukemia cell lines.
CD47 activation through the C-terminus of thrombospondin-1 or its derived peptides (4N1K and PKHB1) induce regulated cell death (RCD) in several types of cancer. Recently, it was demonstrated that PKHB1, the first serum-stable CD47 agonist peptide, induce caspase-independent, calcium-dependent RCD i...
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| Format: | Tesis |
| Language: | English |
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2017
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| Online Access: | http://eprints.uanl.mx/14460/1/1080252237.pdf |