Myocardial perfusion in patients with ST depression during the recovery phase of treadmill stress tests

Objectives: To determine the incidence and characteristics of myocardial perfusion abnormalities in patients with ST depression in recovery only, using Tc-99m gated-SPECT. Background: The significance of ST depression in recovery only after exercise treadmill testing (ETT) remains controversial. Su...

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Main Authors: Peña Almaguer, Erasmo de la, Desai, Milind Y., Mannting, Finn
Format: Article
Language:English
Published: UANL Facultad de Medicina 2009
Online Access:http://eprints.uanl.mx/8830/1/Myocardial%20perfusion%20in%20patients.pdf
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author Peña Almaguer, Erasmo de la
Desai, Milind Y.
Mannting, Finn
author_facet Peña Almaguer, Erasmo de la
Desai, Milind Y.
Mannting, Finn
author_sort Peña Almaguer, Erasmo de la
collection Repositorio Institucional
description Objectives: To determine the incidence and characteristics of myocardial perfusion abnormalities in patients with ST depression in recovery only, using Tc-99m gated-SPECT. Background: The significance of ST depression in recovery only after exercise treadmill testing (ETT) remains controversial. Such finding has been classified as a false positive, false negative and inconclusive sign of CAD. Methods: Fifty patients who underwent ETT and Tc-99m gated-SPECT and demonstrated ST depression only in recovery were analyzed. The group consisted of 28 men and 22 females, mean age of 61 ± 9 years. Perfusion abnormalities, reverse redistribution, heart/lung ratio, changes in LV cavity size and global function were assessed. Results: The mean peak heart rate (PHR) was 139 ± 18 bpm (88% ± 14 of the predicted maximal heart rate). Sixty % of the patients had evidence of CAD in form of either fixed or reversible perfusion abnormalities. Fixed only perfusion abnormalities were found in 3 patients (6%), seven (14%) had fixed and reversible perfusion defects and 20 (40%) showed ischemia only. Ischemia was observed in the anterior wall in 10 patients, inferior wall in 12, lateral wall in 5, apex in 8 and septum in 1 patient. Mean extent of the perfusion abnormalities were 3.7 segments (out of 20) ± 2. Conclusions: Evidence of CAD was found in 60% of the patients with ST depression in recovery only. The most common finding was ischemia in 54% of the patients, and the anterior and inferior walls were most frequently involved. The mean extent of myocardial involvement was moderate, which implies prognostic significance.
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spelling eprints-88302016-01-19T04:07:55Z http://eprints.uanl.mx/8830/ Myocardial perfusion in patients with ST depression during the recovery phase of treadmill stress tests Peña Almaguer, Erasmo de la Desai, Milind Y. Mannting, Finn Objectives: To determine the incidence and characteristics of myocardial perfusion abnormalities in patients with ST depression in recovery only, using Tc-99m gated-SPECT. Background: The significance of ST depression in recovery only after exercise treadmill testing (ETT) remains controversial. Such finding has been classified as a false positive, false negative and inconclusive sign of CAD. Methods: Fifty patients who underwent ETT and Tc-99m gated-SPECT and demonstrated ST depression only in recovery were analyzed. The group consisted of 28 men and 22 females, mean age of 61 ± 9 years. Perfusion abnormalities, reverse redistribution, heart/lung ratio, changes in LV cavity size and global function were assessed. Results: The mean peak heart rate (PHR) was 139 ± 18 bpm (88% ± 14 of the predicted maximal heart rate). Sixty % of the patients had evidence of CAD in form of either fixed or reversible perfusion abnormalities. Fixed only perfusion abnormalities were found in 3 patients (6%), seven (14%) had fixed and reversible perfusion defects and 20 (40%) showed ischemia only. Ischemia was observed in the anterior wall in 10 patients, inferior wall in 12, lateral wall in 5, apex in 8 and septum in 1 patient. Mean extent of the perfusion abnormalities were 3.7 segments (out of 20) ± 2. Conclusions: Evidence of CAD was found in 60% of the patients with ST depression in recovery only. The most common finding was ischemia in 54% of the patients, and the anterior and inferior walls were most frequently involved. The mean extent of myocardial involvement was moderate, which implies prognostic significance. UANL Facultad de Medicina 2009 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/8830/1/Myocardial%20perfusion%20in%20patients.pdf http://eprints.uanl.mx/8830/1.haspreviewThumbnailVersion/Myocardial%20perfusion%20in%20patients.pdf Peña Almaguer, Erasmo de la y Desai, Milind Y. y Mannting, Finn (2009) Myocardial perfusion in patients with ST depression during the recovery phase of treadmill stress tests. Medicina universitaria, 11 (42). pp. 22-28. ISSN 1665-5796
spellingShingle Peña Almaguer, Erasmo de la
Desai, Milind Y.
Mannting, Finn
Myocardial perfusion in patients with ST depression during the recovery phase of treadmill stress tests
thumbnail https://rediab.uanl.mx/themes/sandal5/images/online.png
title Myocardial perfusion in patients with ST depression during the recovery phase of treadmill stress tests
title_full Myocardial perfusion in patients with ST depression during the recovery phase of treadmill stress tests
title_fullStr Myocardial perfusion in patients with ST depression during the recovery phase of treadmill stress tests
title_full_unstemmed Myocardial perfusion in patients with ST depression during the recovery phase of treadmill stress tests
title_short Myocardial perfusion in patients with ST depression during the recovery phase of treadmill stress tests
title_sort myocardial perfusion in patients with st depression during the recovery phase of treadmill stress tests
url http://eprints.uanl.mx/8830/1/Myocardial%20perfusion%20in%20patients.pdf
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