Predictors of in-hospital mortality in patients with non-variceal upper gastrointestinal bleeding
Objective: to determine the independent predictors of in-hospital death of Hispanic patients with nonvariceal upper gastrointestinal bleeding (NVUGB). Experimental design: prospective and observational trial. Patients: in a period between 2000 and 2009, all patients with NVUGB admitted to our hospit...
| Autores principales: | , , , , , , , , |
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| Formato: | Artículo |
| Lenguaje: | inglés |
| Publicado: |
Sociedad Española de Patología Digestiva
2011
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| Acceso en línea: | http://eprints.uanl.mx/30198/1/30198.pdf |
| _version_ | 1838551030079422464 |
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| author | González González, José Alberto Vázquez Elizondo, Genaro García Compeán, Diego Obed Gaytán Torres, Juan Flores Rendón, Ángel Ricardo Jáquez Quintana, Joel Omar Garza Galindo, Aldo Azael Cárdenas Sandoval, Martha Graciela Maldonado Garza, Héctor Jesús |
| author_facet | González González, José Alberto Vázquez Elizondo, Genaro García Compeán, Diego Obed Gaytán Torres, Juan Flores Rendón, Ángel Ricardo Jáquez Quintana, Joel Omar Garza Galindo, Aldo Azael Cárdenas Sandoval, Martha Graciela Maldonado Garza, Héctor Jesús |
| author_sort | González González, José Alberto |
| collection | Repositorio Institucional |
| description | Objective: to determine the independent predictors of in-hospital death of Hispanic patients with nonvariceal upper gastrointestinal bleeding (NVUGB). Experimental design: prospective and observational trial. Patients: in a period between 2000 and 2009, all patients with NVUGB admitted to our hospital were studied. Demographical and clinical characteristics, endoscopic findings and laboratory tests were evaluated. χ² and Mann-Whitney U analyses were performed for comparisons, and binary logistic regression was employed to identify independent predictors of in-hospital mortality. Results: 1,067 patients were included, 65% male with a mean age of 58.8 years. Mean number of comorbidities per patient was 1.6 ± 0.76. The most frequent cause of bleeding were gastric and duodenal ulcers (55.4%); 278 patients (25.8%) received endoscopic treatment of which 69.1% had combined therapy. Rebleeding occurred in 36 patients (3.4%) of which 50% died. Inhospital mortality was 10.2%, of which only 3.1% was associated to bleeding. When comparing causes of death among patients with and without comorbidities, only hypovolemic shock was found significative (48.3 vs. 25%; p = 0.020). Binary logistic regression found that the number of comorbidities, Rockall scale serum albumin < 2.6 g/dL on admission; rebleeding and length of hospital stay were independent risk factors of in-hospital mortality. Conclusion: the number of comorbidities, the Rockall scale score, an albumin level < 2.6 g/dL, the presence of rebleeding and hospital stay were predictors of in-hospital mortality in patients with UNVGB. |
| format | Article |
| id | eprints-30198 |
| institution | UANL |
| language | English |
| publishDate | 2011 |
| publisher | Sociedad Española de Patología Digestiva |
| record_format | eprints |
| spelling | eprints-301982025-07-07T16:02:49Z http://eprints.uanl.mx/30198/ Predictors of in-hospital mortality in patients with non-variceal upper gastrointestinal bleeding González González, José Alberto Vázquez Elizondo, Genaro García Compeán, Diego Obed Gaytán Torres, Juan Flores Rendón, Ángel Ricardo Jáquez Quintana, Joel Omar Garza Galindo, Aldo Azael Cárdenas Sandoval, Martha Graciela Maldonado Garza, Héctor Jesús Objective: to determine the independent predictors of in-hospital death of Hispanic patients with nonvariceal upper gastrointestinal bleeding (NVUGB). Experimental design: prospective and observational trial. Patients: in a period between 2000 and 2009, all patients with NVUGB admitted to our hospital were studied. Demographical and clinical characteristics, endoscopic findings and laboratory tests were evaluated. χ² and Mann-Whitney U analyses were performed for comparisons, and binary logistic regression was employed to identify independent predictors of in-hospital mortality. Results: 1,067 patients were included, 65% male with a mean age of 58.8 years. Mean number of comorbidities per patient was 1.6 ± 0.76. The most frequent cause of bleeding were gastric and duodenal ulcers (55.4%); 278 patients (25.8%) received endoscopic treatment of which 69.1% had combined therapy. Rebleeding occurred in 36 patients (3.4%) of which 50% died. Inhospital mortality was 10.2%, of which only 3.1% was associated to bleeding. When comparing causes of death among patients with and without comorbidities, only hypovolemic shock was found significative (48.3 vs. 25%; p = 0.020). Binary logistic regression found that the number of comorbidities, Rockall scale serum albumin < 2.6 g/dL on admission; rebleeding and length of hospital stay were independent risk factors of in-hospital mortality. Conclusion: the number of comorbidities, the Rockall scale score, an albumin level < 2.6 g/dL, the presence of rebleeding and hospital stay were predictors of in-hospital mortality in patients with UNVGB. Sociedad Española de Patología Digestiva 2011 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/30198/1/30198.pdf http://eprints.uanl.mx/30198/1.haspreviewThumbnailVersion/30198.pdf González González, José Alberto y Vázquez Elizondo, Genaro y García Compeán, Diego y Obed Gaytán Torres, Juan y Flores Rendón, Ángel Ricardo y Jáquez Quintana, Joel Omar y Garza Galindo, Aldo Azael y Cárdenas Sandoval, Martha Graciela y Maldonado Garza, Héctor Jesús (2011) Predictors of in-hospital mortality in patients with non-variceal upper gastrointestinal bleeding. Revista Española de Enfermedades Digestivas, 103 (4). pp. 196-203. ISSN 1130-0108 doi:10.4321/S1130-01082011000400005 |
| spellingShingle | González González, José Alberto Vázquez Elizondo, Genaro García Compeán, Diego Obed Gaytán Torres, Juan Flores Rendón, Ángel Ricardo Jáquez Quintana, Joel Omar Garza Galindo, Aldo Azael Cárdenas Sandoval, Martha Graciela Maldonado Garza, Héctor Jesús Predictors of in-hospital mortality in patients with non-variceal upper gastrointestinal bleeding |
| thumbnail | https://rediab.uanl.mx/themes/sandal5/images/online.png |
| title | Predictors of in-hospital mortality in patients with non-variceal upper gastrointestinal bleeding |
| title_full | Predictors of in-hospital mortality in patients with non-variceal upper gastrointestinal bleeding |
| title_fullStr | Predictors of in-hospital mortality in patients with non-variceal upper gastrointestinal bleeding |
| title_full_unstemmed | Predictors of in-hospital mortality in patients with non-variceal upper gastrointestinal bleeding |
| title_short | Predictors of in-hospital mortality in patients with non-variceal upper gastrointestinal bleeding |
| title_sort | predictors of in hospital mortality in patients with non variceal upper gastrointestinal bleeding |
| url | http://eprints.uanl.mx/30198/1/30198.pdf |
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