Preventing bisphosphonate induced osteonecrosis of the jaw with a polyguanidine conjugate (GuaDex): a promising new approach

Osteonecrosis of the jaw (ONJ) is a relatively rare side effect after prolonged use of bisphosphonates, which are drugs used to treat bone resorption in osteoporosis and certain cancers. This study introduces a novel ONJ model in rats by combining exposure to bisphosphonates, oral surgery, and bacte...

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Bibliographic Details

Main Authors:	Cantorán Castillo, Arquímedes, Beltrán Salinas, Belinda, Antúnez Treviño, Jorge M., Martínez Pedraza, Ricardo, Franco Márquez, Rodolfo, Guzmán García, Mario A., Cerda Flores, Ricardo Martín, Perales Pérez, Raúl Vicente, Zakian, Christian, Ancer Rodríguez, Jesús, Márquez Méndez, Marcela
Format:	Article
Language:	English
Published:	Elsevier 2024
Online Access:	http://eprints.uanl.mx/30035/1/30035.pdf