Insoluble chitosan complex as a potential adsorbent for aflatoxin B1 in poultry feed
As a class of secondary metabolites or toxins produced by fungi, aflatoxins can poison humans and animals; among them, aflatoxin B1 (AFB1) is the most dangerous one owing to its carcinogenic and mutagenic properties that increase risks for hepatocellular carcinoma in humans; hence, adsorbents such a...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media
2022
|
| Online Access: | http://eprints.uanl.mx/30027/1/30027.pdf |
| _version_ | 1836397364614529024 |
|---|---|
| author | Delgado Cedeño, Armando Hernández Martínez, Sara Paola Ramos Zayas, Yareellys Marroquín Cardona, Alicia Guadalupe Méndez Zamora, Gerardo Franco Molina, Moisés Armides Kawas, Jorge R. |
| author_facet | Delgado Cedeño, Armando Hernández Martínez, Sara Paola Ramos Zayas, Yareellys Marroquín Cardona, Alicia Guadalupe Méndez Zamora, Gerardo Franco Molina, Moisés Armides Kawas, Jorge R. |
| author_sort | Delgado Cedeño, Armando |
| collection | Repositorio Institucional |
| description | As a class of secondary metabolites or toxins produced by fungi, aflatoxins can poison humans and animals; among them, aflatoxin B1 (AFB1) is the most dangerous one owing to its carcinogenic and mutagenic properties that increase risks for hepatocellular carcinoma in humans; hence, adsorbents such as smectites are commonly included in poultry feed to mitigate their effects. In this study, chitosan was crosslinked with sodium dodecyl sulfate (SDS) to form an insoluble polymer complex that is stable at the relevant physiological pH levels. The characterization via Fourier transforms infrared spectroscopy revealed the interaction between the sulfate groups of the SDS and the amine group of chitosan (1,016 and 819 cm−1 ); this result was further confirmed by the X-ray diffraction patterns with a change in the crystalline structure of the chitosan-insoluble complex (2θ = 4.76°, 7°, and 22°). The morphology of the chitosan-insoluble complex obtained using a field emission scanning electron microscope (FE-SEM) revealed that particles were slightly porous. After characterization, the performance of the chemically modified polymer complex was evaluated as an adsorbent for AFB1 and compared with those of the unmodified chitosan, soluble chitosan complex, and commercial montmorillonite clay binder. In addition, the polymer complex was investigated as an adsorbent in an in vitro model for the poultry gastrointestinal system. Sequestration of AFB1 by a chemically modified polymer complex was 93.4%, equivalent to that of commercial
montmorillonite clay (99.5%). However, these treatments also sequestered microminerals, particularly selenium and iron. This pH-stable, high-capacity adsorbent could be used in poultry feed to reduce the uptake of AFB1. |
| format | Article |
| id | eprints-30027 |
| institution | UANL |
| language | English |
| publishDate | 2022 |
| publisher | Frontiers Media |
| record_format | eprints |
| spelling | eprints-300272025-06-26T16:17:26Z http://eprints.uanl.mx/30027/ Insoluble chitosan complex as a potential adsorbent for aflatoxin B1 in poultry feed Delgado Cedeño, Armando Hernández Martínez, Sara Paola Ramos Zayas, Yareellys Marroquín Cardona, Alicia Guadalupe Méndez Zamora, Gerardo Franco Molina, Moisés Armides Kawas, Jorge R. As a class of secondary metabolites or toxins produced by fungi, aflatoxins can poison humans and animals; among them, aflatoxin B1 (AFB1) is the most dangerous one owing to its carcinogenic and mutagenic properties that increase risks for hepatocellular carcinoma in humans; hence, adsorbents such as smectites are commonly included in poultry feed to mitigate their effects. In this study, chitosan was crosslinked with sodium dodecyl sulfate (SDS) to form an insoluble polymer complex that is stable at the relevant physiological pH levels. The characterization via Fourier transforms infrared spectroscopy revealed the interaction between the sulfate groups of the SDS and the amine group of chitosan (1,016 and 819 cm−1 ); this result was further confirmed by the X-ray diffraction patterns with a change in the crystalline structure of the chitosan-insoluble complex (2θ = 4.76°, 7°, and 22°). The morphology of the chitosan-insoluble complex obtained using a field emission scanning electron microscope (FE-SEM) revealed that particles were slightly porous. After characterization, the performance of the chemically modified polymer complex was evaluated as an adsorbent for AFB1 and compared with those of the unmodified chitosan, soluble chitosan complex, and commercial montmorillonite clay binder. In addition, the polymer complex was investigated as an adsorbent in an in vitro model for the poultry gastrointestinal system. Sequestration of AFB1 by a chemically modified polymer complex was 93.4%, equivalent to that of commercial montmorillonite clay (99.5%). However, these treatments also sequestered microminerals, particularly selenium and iron. This pH-stable, high-capacity adsorbent could be used in poultry feed to reduce the uptake of AFB1. Frontiers Media 2022 Article PeerReviewed text en cc_by_nc_nd http://eprints.uanl.mx/30027/1/30027.pdf http://eprints.uanl.mx/30027/1.haspreviewThumbnailVersion/30027.pdf Delgado Cedeño, Armando y Hernández Martínez, Sara Paola y Ramos Zayas, Yareellys y Marroquín Cardona, Alicia Guadalupe y Méndez Zamora, Gerardo y Franco Molina, Moisés Armides y Kawas, Jorge R. (2022) Insoluble chitosan complex as a potential adsorbent for aflatoxin B1 in poultry feed. Frontiers in Materials, 9. pp. 1-14. ISSN 2296-8016 doi:10.3389/fmats.2022.1044495 |
| spellingShingle | Delgado Cedeño, Armando Hernández Martínez, Sara Paola Ramos Zayas, Yareellys Marroquín Cardona, Alicia Guadalupe Méndez Zamora, Gerardo Franco Molina, Moisés Armides Kawas, Jorge R. Insoluble chitosan complex as a potential adsorbent for aflatoxin B1 in poultry feed |
| thumbnail | https://rediab.uanl.mx/themes/sandal5/images/online.png |
| title | Insoluble chitosan complex as a potential adsorbent for aflatoxin B1 in poultry feed |
| title_full | Insoluble chitosan complex as a potential adsorbent for aflatoxin B1 in poultry feed |
| title_fullStr | Insoluble chitosan complex as a potential adsorbent for aflatoxin B1 in poultry feed |
| title_full_unstemmed | Insoluble chitosan complex as a potential adsorbent for aflatoxin B1 in poultry feed |
| title_short | Insoluble chitosan complex as a potential adsorbent for aflatoxin B1 in poultry feed |
| title_sort | insoluble chitosan complex as a potential adsorbent for aflatoxin b1 in poultry feed |
| url | http://eprints.uanl.mx/30027/1/30027.pdf |
| work_keys_str_mv | AT delgadocedenoarmando insolublechitosancomplexasapotentialadsorbentforaflatoxinb1inpoultryfeed AT hernandezmartinezsarapaola insolublechitosancomplexasapotentialadsorbentforaflatoxinb1inpoultryfeed AT ramoszayasyareellys insolublechitosancomplexasapotentialadsorbentforaflatoxinb1inpoultryfeed AT marroquincardonaaliciaguadalupe insolublechitosancomplexasapotentialadsorbentforaflatoxinb1inpoultryfeed AT mendezzamoragerardo insolublechitosancomplexasapotentialadsorbentforaflatoxinb1inpoultryfeed AT francomolinamoisesarmides insolublechitosancomplexasapotentialadsorbentforaflatoxinb1inpoultryfeed AT kawasjorger insolublechitosancomplexasapotentialadsorbentforaflatoxinb1inpoultryfeed |